decreased heart rate Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005333
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Genes

87 gene mutations causing the decreased heart rate phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACADVL acyl-CoA dehydrogenase, very long chain
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRA1B adrenoceptor alpha 1B
AGTR1 angiotensin II receptor, type 1
AKAP10 A kinase (PRKA) anchor protein 10
ARID1A AT rich interactive domain 1A (SWI-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
BMP10 bone morphogenetic protein 10
BRAF B-Raf proto-oncogene, serine/threonine kinase
BVES blood vessel epicardial substance
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CALCB calcitonin-related polypeptide beta
CASQ2 calsequestrin 2 (cardiac muscle)
CDH23 cadherin-related 23
CLOCK clock circadian regulator
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DLL1 delta-like 1 (Drosophila)
EFNA1 ephrin-A1
EPAS1 endothelial PAS domain protein 1
EPHA3 EPH receptor A3
FFAR3 free fatty acid receptor 3
FOXP1 forkhead box P1
GBE1 glucan (1,4-alpha-), branching enzyme 1
GJA1 gap junction protein, alpha 1, 43kDa
GLA galactosidase, alpha
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HDAC2 histone deacetylase 2
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
IGHMBP2 immunoglobulin mu binding protein 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KEL Kell blood group, metallo-endopeptidase
KL klotho
LAMA4 laminin, alpha 4
LEPR leptin receptor
LMNA lamin A/C
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MEF2A myocyte enhancer factor 2A
MRVI1 murine retrovirus integration site 1 homolog
NCOR1 nuclear receptor corepressor 1
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NOS3 nitric oxide synthase 3 (endothelial cell)
NPAS2 neuronal PAS domain protein 2
NPY1R neuropeptide Y receptor Y1
NRG1 neuregulin 1
NTF3 neurotrophin 3
NUCB2 nucleobindin 2
PDC phosducin
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
POPDC2 popeye domain containing 2
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PTS 6-pyruvoyltetrahydropterin synthase
PZP pregnancy-zone protein
RGS6 regulator of G-protein signaling 6
RXRA retinoid X receptor, alpha
RYR2 ryanodine receptor 2 (cardiac)
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SH3PXD2B SH3 and PX domains 2B
SHOX2 short stature homeobox 2
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMN1 survival of motor neuron 1, telomeric
SP4 Sp4 transcription factor
SYNE1 spectrin repeat containing, nuclear envelope 1
TBX3 T-box 3
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TGFB1 transforming growth factor, beta 1
TH tyrosine hydroxylase
THBS1 thrombospondin 1
THRA thyroid hormone receptor, alpha
VEGFA vascular endothelial growth factor A
ZFPM2 zinc finger protein, FOG family member 2
ZRANB2 zinc finger, RAN-binding domain containing 2