decreased gonadotroph cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced number of the anterior pituitary cells that can produce both follicle stimulating hormone (FSH) and luteinizing hormone (LH) (Mammalian Phenotype Ontology, MP_0008335)
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10 gene mutations causing the decreased gonadotroph cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
DRD2 dopamine receptor D2
IRS2 insulin receptor substrate 2
LHX3 LIM homeobox 3
LHX4 LIM homeobox 4
NR5A1 nuclear receptor subfamily 5, group A, member 1
OTX2 orthodenticle homeobox 2
PITX1 paired-like homeodomain 1
PITX2 paired-like homeodomain 2
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
WNT4 wingless-type MMTV integration site family, member 4