decreased gamma-delta t cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced number of immature or mature T cells expressing an gamma-delta T cell receptor complex (Mammalian Phenotype Ontology, MP_0008347)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008347
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Genes

30 gene mutations causing the decreased gamma-delta t cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
CARD11 caspase recruitment domain family, member 11
CCL25 chemokine (C-C motif) ligand 25
CCR10 chemokine (C-C motif) receptor 10
CCR9 chemokine (C-C motif) receptor 9
CD247 CD247 molecule
DCBLD2 discoidin, CUB and LCCL domain containing 2
DNTT DNA nucleotidylexotransferase
FYN FYN proto-oncogene, Src family tyrosine kinase
GATA3 GATA binding protein 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL17A interleukin 17A
IL17F interleukin 17F
IL1RL2 interleukin 1 receptor-like 2
IL23A interleukin 23, alpha subunit p19
IL2RG interleukin 2 receptor, gamma
IL7R interleukin 7 receptor
JAG2 jagged 2
LAT linker for activation of T cells
LCK LCK proto-oncogene, Src family tyrosine kinase
NCKAP1L NCK-associated protein 1-like
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NLK nemo-like kinase
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTPRC protein tyrosine phosphatase, receptor type, C
RAG1 recombination activating gene 1
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
SOX13 SRY (sex determining region Y)-box 13