decreased forebrain size Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description size reduction or truncation of the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions) (Mammalian Phenotype Ontology, MP_0012138)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0012138
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Genes

37 gene mutations causing the decreased forebrain size phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
ARID1A AT rich interactive domain 1A (SWI-like)
ARNT aryl hydrocarbon receptor nuclear translocator
AXIN1 axin 1
CCNF cyclin F
CNBP CCHC-type zinc finger, nucleic acid binding protein
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXORF56 chromosome X open reading frame 56
CYCS cytochrome c, somatic
DKK1 dickkopf WNT signaling pathway inhibitor 1
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
ERF Ets2 repressor factor
FOXG1 forkhead box G1
HESX1 HESX homeobox 1
HHEX hematopoietically expressed homeobox
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
KIF20B kinesin family member 20B
LHX2 LIM homeobox 2
LIAS lipoic acid synthetase
LRP6 low density lipoprotein receptor-related protein 6
MBOAT7 membrane bound O-acyltransferase domain containing 7
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NR2E1 nuclear receptor subfamily 2, group E, member 1
OTX2 orthodenticle homeobox 2
PAK1IP1 PAK1 interacting protein 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PHGDH phosphoglycerate dehydrogenase
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
SETD2 SET domain containing 2
SIX3 SIX homeobox 3
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TDGF1 teratocarcinoma-derived growth factor 1
TMEM67 transmembrane protein 67
TULP3 tubby like protein 3
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble