decreased food intake Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the total number of calories/food amount taken in over time when compared to the normal state (Mammalian Phenotype Ontology, MP_0011940)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011940
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Genes

65 gene mutations causing the decreased food intake phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
AGRP agouti related neuropeptide
ARID5B AT rich interactive domain 5B (MRF1-like)
ATN1 atrophin 1
CALCB calcitonin-related polypeptide beta
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CHRM3 cholinergic receptor, muscarinic 3
CIDEB cell death-inducing DFFA-like effector b
CISD2 CDGSH iron sulfur domain 2
CPT1C carnitine palmitoyltransferase 1C
CTF1 cardiotrophin 1
CXCL14 chemokine (C-X-C motif) ligand 14
DLL1 delta-like 1 (Drosophila)
DMBX1 diencephalon/mesencephalon homeobox 1
DRD2 dopamine receptor D2
FADS2 fatty acid desaturase 2
FTO fat mass and obesity associated
GALP galanin-like peptide
GHSR growth hormone secretagogue receptor
GLP1R glucagon-like peptide 1 receptor
GPR39 G protein-coupled receptor 39
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HNF4G hepatocyte nuclear factor 4, gamma
HRH1 histamine receptor H1
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KRT6B keratin 6B, type II
LEP leptin
MAGEL2 melanoma antigen family L2
MAPK8 mitogen-activated protein kinase 8
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MC3R melanocortin 3 receptor
MYH1 myosin, heavy chain 1, skeletal muscle, adult
NEGR1 neuronal growth regulator 1
NMUR2 neuromedin U receptor 2
NPC1 Niemann-Pick disease, type C1
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OXT oxytocin/neurophysin I prepropeptide
PDE10A phosphodiesterase 10A
PHOSPHO1 phosphatase, orphan 1
PLIN2 perilipin 2
PMCH pro-melanin-concentrating hormone
POMC proopiomelanocortin
PPARG peroxisome proliferator-activated receptor gamma
PRCP prolylcarboxypeptidase (angiotensinase C)
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRLHR prolactin releasing hormone receptor
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RCAN2 regulator of calcineurin 2
RMI1 RecQ mediated genome instability 1
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC30A7 solute carrier family 30 (zinc transporter), member 7
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
THRA thyroid hormone receptor, alpha
TRIB2 tribbles pseudokinase 2
UBB ubiquitin B
UCN2 urocortin 2
VIPR2 vasoactive intestinal peptide receptor 2