decreased fibroblast cell migration Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced frequency of or less rapid fibroblast cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium (Mammalian Phenotype Ontology, MP_0011708)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011708
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Genes

29 gene mutations causing the decreased fibroblast cell migration phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARID5B AT rich interactive domain 5B (MRF1-like)
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
CYLD cylindromatosis (turban tumor syndrome)
EGFR epidermal growth factor receptor
EHD1 EH-domain containing 1
FLNB filamin B, beta
FNDC3B fibronectin type III domain containing 3B
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MRC2 mannose receptor, C type 2
MTSS1 metastasis suppressor 1
NCOA3 nuclear receptor coactivator 3
PALLD palladin, cytoskeletal associated protein
PLEC plectin
PTK2 protein tyrosine kinase 2
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RHOB ras homolog family member B
S1PR1 sphingosine-1-phosphate receptor 1
SCHIP1 schwannomin interacting protein 1
SDC4 syndecan 4
SGPL1 sphingosine-1-phosphate lyase 1
SYNE2 spectrin repeat containing, nuclear envelope 2
TGS1 trimethylguanosine synthase 1
WDPCP WD repeat containing planar cell polarity effector
ZFAND5 zinc finger, AN1-type domain 5
ZYX zyxin