decreased fertilization frequency Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description the number of secondary oocytes each penetrated by a spermatozoon followed by fusion of the male and female pronuclei are fewer than expected (Mammalian Phenotype Ontology, MP_0009647)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009647
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Genes

16 gene mutations causing the decreased fertilization frequency phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AHR aryl hydrocarbon receptor
C1ORF56 chromosome 1 open reading frame 56
CSF1 colony stimulating factor 1 (macrophage)
DKKL1 dickkopf-like 1
EPHB6 EPH receptor B6
GOLGA3 golgin A3
GPX4 glutathione peroxidase 4
NOS3 nitric oxide synthase 3 (endothelial cell)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PLA2G3 phospholipase A2, group III
PRSS21 protease, serine, 21 (testisin)
SPESP1 sperm equatorial segment protein 1
TEX101 testis expressed 101
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTLL5 tubulin tyrosine ligase-like family member 5