decreased fatty acid level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the concentration of aliphatic monocarboxylic acids derived from or contained in esterified form in an animal or vegetable fat, oil or wax; natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated (Mammalian Phenotype Ontology, MP_0005282)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005282
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Genes

87 gene mutations causing the decreased fatty acid level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABHD5 abhydrolase domain containing 5
ACACB acetyl-CoA carboxylase beta
ACOT13 acyl-CoA thioesterase 13
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACTB actin, beta
ADRA1B adrenoceptor alpha 1B
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AHSG alpha-2-HS-glycoprotein
AMACR alpha-methylacyl-CoA racemase
ANGPTL3 angiopoietin-like 3
APOA2 apolipoprotein A-II
BBS12 Bardet-Biedl syndrome 12
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL13 chemokine (C-C motif) ligand 13
CD36 CD36 molecule (thrombospondin receptor)
CDH23 cadherin-related 23
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CES1 carboxylesterase 1
CHD7 chromodomain helicase DNA binding protein 7
CIDEA cell death-inducing DFFA-like effector a
CIDEB cell death-inducing DFFA-like effector b
CIDEC cell death-inducing DFFA-like effector c
COQ4 coenzyme Q4
CRBN cereblon
CREBBP CREB binding protein
CRHR2 corticotropin releasing hormone receptor 2
CRTC1 CREB regulated transcription coactivator 1
CRTC3 CREB regulated transcription coactivator 3
CTF1 cardiotrophin 1
DGAT2 diacylglycerol O-acyltransferase 2
DIXDC1 DIX domain containing 1
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DNAJC5G DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
DUSP1 dual specificity phosphatase 1
ELOVL2 ELOVL fatty acid elongase 2
FABP3 fatty acid binding protein 3, muscle and heart
FABP7 fatty acid binding protein 7, brain
FADS2 fatty acid desaturase 2
FGF21 fibroblast growth factor 21
FGL1 fibrinogen-like 1
FOXO1 forkhead box O1
HNF4A hepatocyte nuclear factor 4, alpha
IFT80 intraflagellar transport 80
INPP5K inositol polyphosphate-5-phosphatase K
INPPL1 inositol polyphosphate phosphatase-like 1
LIPE lipase, hormone-sensitive
LPIN1 lipin 1
MBOAT7 membrane bound O-acyltransferase domain containing 7
MGLL monoglyceride lipase
MLXIPL MLX interacting protein-like
MYO7A myosin VIIA
NCOA3 nuclear receptor coactivator 3
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR1H4 nuclear receptor subfamily 1, group H, member 4
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
NUAK2 NUAK family, SNF1-like kinase, 2
OED Oregon eye disease
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PEX1 peroxisomal biogenesis factor 1
PEX7 peroxisomal biogenesis factor 7
PHYH phytanoyl-CoA 2-hydroxylase
PLIN2 perilipin 2
PLIN5 perilipin 5
PNPLA2 patatin-like phospholipase domain containing 2
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RNF7 ring finger protein 7
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCP2 sterol carrier protein 2
SIRT6 sirtuin 6
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SRA1 steroid receptor RNA activator 1
STARD10 StAR-related lipid transfer (START) domain containing 10
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
THEM5 thioesterase superfamily member 5
THRB thyroid hormone receptor, beta
TNF tumor necrosis factor
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)