decreased exploration in new environment Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less amount of time spent investigating a new location (Mammalian Phenotype Ontology, MP_0001417)
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78 gene mutations causing the decreased exploration in new environment phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ADORA2A adenosine A2a receptor
ADRA1B adrenoceptor alpha 1B
AGTR2 angiotensin II receptor, type 2
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARSG arylsulfatase G
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATXN1 ataxin 1
ATXN3 ataxin 3
BACE1 beta-site APP-cleaving enzyme 1
BDNF brain-derived neurotrophic factor
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CADPS2 Ca++-dependent secretion activator 2
CAV1 caveolin 1, caveolae protein, 22kDa
CHRD chordin
CKMT1A creatine kinase, mitochondrial 1A
CNR1 cannabinoid receptor 1 (brain)
CPLX2 complexin 2
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DRD4 dopamine receptor D4
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERCC2 excision repair cross-complementation group 2
ESR2 estrogen receptor 2 (ER beta)
FOXP2 forkhead box P2
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRID2 glutamate receptor, ionotropic, delta 2
GRM1 glutamate receptor, metabotropic 1
GRM8 glutamate receptor, metabotropic 8
GSK3B glycogen synthase kinase 3 beta
GTF2I general transcription factor IIi
HDC histidine decarboxylase
HIPK2 homeodomain interacting protein kinase 2
HPRT1 hypoxanthine phosphoribosyltransferase 1
HRH1 histamine receptor H1
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
LRRN1 leucine rich repeat neuronal 1
LRRTM1 leucine rich repeat transmembrane neuronal 1
MAGED1 melanoma antigen family D1
MAN2B1 mannosidase, alpha, class 2B, member 1
MAP1B microtubule-associated protein 1B
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MPST mercaptopyruvate sulfurtransferase
NAV2 neuron navigator 2
NOTCH3 notch 3
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
NR2E1 nuclear receptor subfamily 2, group E, member 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PDE10A phosphodiesterase 10A
PITX3 paired-like homeodomain 3
PLAT plasminogen activator, tissue
PLAUR plasminogen activator, urokinase receptor
RALBP1 ralA binding protein 1
RGS7 regulator of G-protein signaling 7
RORB RAR-related orphan receptor B
RTN4R reticulon 4 receptor
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SHANK3 SH3 and multiple ankyrin repeat domains 3
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SP4 Sp4 transcription factor
SPPL3 signal peptide peptidase like 3
SSTR2 somatostatin receptor 2
TRIB2 tribbles pseudokinase 2
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
WFS1 Wolfram syndrome 1 (wolframin)
ZDHHC8 zinc finger, DHHC-type containing 8
ZMIZ2 zinc finger, MIZ-type containing 2