decreased eosinophil cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description fewer than normal eosinophil numbers (Mammalian Phenotype Ontology, MP_0005012)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005012
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Genes

41 gene mutations causing the decreased eosinophil cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACVR2A activin A receptor, type IIA
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BHLHE41 basic helix-loop-helix family, member e41
C3AR1 complement component 3a receptor 1
CCL11 chemokine (C-C motif) ligand 11
CCR3 chemokine (C-C motif) receptor 3
CCR4 chemokine (C-C motif) receptor 4
CD34 CD34 molecule
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
EP300 E1A binding protein p300
FAS Fas cell surface death receptor
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
GADD45A growth arrest and DNA-damage-inducible, alpha
GALC galactosylceramidase
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GPC2 glypican 2
IL13 interleukin 13
IL17RB interleukin 17 receptor B
IL1R1 interleukin 1 receptor, type I
IL1RL1 interleukin 1 receptor-like 1
IL21R interleukin 21 receptor
IL25 interleukin 25
IL33 interleukin 33
IL4 interleukin 4
IL5 interleukin 5
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB7 integrin, beta 7
KISS1R KISS1 receptor
LTB4R leukotriene B4 receptor
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MINA MYC induced nuclear antigen
MYB v-myb avian myeloblastosis viral oncogene homolog
NOS2 nitric oxide synthase 2, inducible
PLA2G10 phospholipase A2, group X
SOCS1 suppressor of cytokine signaling 1
TBK1 TANK-binding kinase 1
TRIB1 tribbles pseudokinase 1