decreased dn3 thymocyte number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced number of thymocytes that have the cell surface marker phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-negative and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain. (Mammalian Phenotype Ontology, MP_0010134)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010134
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Genes

3 gene mutations causing the decreased dn3 thymocyte number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
IKZF1 IKAROS family zinc finger 1 (Ikaros)
MSI2 musashi RNA-binding protein 2
ZBTB1 zinc finger and BTB domain containing 1