decreased dn1 thymic pro-t cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced number of pro-T cells that have the cell surface marker phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-negative (Mammalian Phenotype Ontology, MP_0010130)
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7 gene mutations causing the decreased dn1 thymic pro-t cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CDK6 cyclin-dependent kinase 6
DCLRE1C DNA cross-link repair 1C
IKZF1 IKAROS family zinc finger 1 (Ikaros)
MCM4 minichromosome maintenance complex component 4
PRKCH protein kinase C, eta
PRKCQ protein kinase C, theta
SYK spleen tyrosine kinase