decreased circulating progesterone level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced blood concentration of the antiestrogenic steroid released by the corpus luteum that stimulates the uterus to prepare for pregnancy (Mammalian Phenotype Ontology, MP_0005185)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005185
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Genes

27 gene mutations causing the decreased circulating progesterone level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AFP alpha-fetoprotein
ARNTL aryl hydrocarbon receptor nuclear translocator-like
CDK4 cyclin-dependent kinase 4
CLOCK clock circadian regulator
CNR1 cannabinoid receptor 1 (brain)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
DDR2 discoidin domain receptor tyrosine kinase 2
ESR1 estrogen receptor 1
FSHB follicle stimulating hormone, beta polypeptide
FSHR follicle stimulating hormone receptor
FZD4 frizzled class receptor 4
GNRHR gonadotropin-releasing hormone receptor
INHBA inhibin, beta A
IRS2 insulin receptor substrate 2
KPNA1 karyopherin alpha 1 (importin alpha 5)
LHB luteinizing hormone beta polypeptide
LHCGR luteinizing hormone/choriogonadotropin receptor
MARK2 MAP/microtubule affinity-regulating kinase 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR5A2 nuclear receptor subfamily 5, group A, member 2
POR P450 (cytochrome) oxidoreductase
PRLR prolactin receptor
RBMS1 RNA binding motif, single stranded interacting protein 1
TIMP1 TIMP metallopeptidase inhibitor 1
TSHR thyroid stimulating hormone receptor