decreased circulating pituitary hormone level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than expected concentration of any of the pituitary hormones found in the blood (Mammalian Phenotype Ontology, MP_0005118)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005118
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Genes

69 gene mutations causing the decreased circulating pituitary hormone level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACVR2A activin A receptor, type IIA
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AMH anti-Mullerian hormone
AR androgen receptor
ASIP agouti signaling protein
AVPR1B arginine vasopressin receptor 1B
BRS3 bombesin-like receptor 3
CDK4 cyclin-dependent kinase 4
CGA glycoprotein hormones, alpha polypeptide
CLOCK clock circadian regulator
CORT cortistatin
CPE carboxypeptidase E
CRTC1 CREB regulated transcription coactivator 1
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DIO3 deiodinase, iodothyronine, type III
DRD2 dopamine receptor D2
ESR1 estrogen receptor 1
FGF21 fibroblast growth factor 21
FOXN1 forkhead box N1
FSHB follicle stimulating hormone, beta polypeptide
GHR growth hormone receptor
GHRHR growth hormone releasing hormone receptor
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRHR gonadotropin-releasing hormone receptor
HMX2 H6 family homeobox 2
HMX3 H6 family homeobox 3
IGF1 insulin-like growth factor 1 (somatomedin C)
INHA inhibin, alpha
IRS2 insulin receptor substrate 2
JUND jun D proto-oncogene
KISS1 KiSS-1 metastasis-suppressor
KISS1R KISS1 receptor
LATS1 large tumor suppressor kinase 1
LHCGR luteinizing hormone/choriogonadotropin receptor
LHX3 LIM homeobox 3
LIF leukemia inhibitory factor
LIN28A lin-28 homolog A (C. elegans)
MARK2 MAP/microtubule affinity-regulating kinase 2
MBOAT4 membrane bound O-acyltransferase domain containing 4
NHLH2 nescient helix loop helix 2
NOS1 nitric oxide synthase 1 (neuronal)
NPC1 Niemann-Pick disease, type C1
NPEPPS aminopeptidase puromycin sensitive
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OTX2 orthodenticle homeobox 2
PAX6 paired box 6
PCSK1 proprotein convertase subtilisin/kexin type 1
PDE8B phosphodiesterase 8B
PGR progesterone receptor
POMC proopiomelanocortin
POU1F1 POU class 1 homeobox 1
PRL prolactin
PROP1 PROP paired-like homeobox 1
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RIMS2 regulating synaptic membrane exocytosis 2
SERP1 stress-associated endoplasmic reticulum protein 1
SIRT1 sirtuin 1
SOCS2 suppressor of cytokine signaling 2
SOD1 superoxide dismutase 1, soluble
SST somatostatin
TBX19 T-box 19
TRH thyrotropin-releasing hormone
TRHR thyrotropin-releasing hormone receptor
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1
VGF VGF nerve growth factor inducible
VIP vasoactive intestinal peptide