decreased circulating interleukin-5 level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the amount in the blood of a cytokine that promotes differentiation and activation of eosinophils; it also triggers activated B-cells to differentiate into immunoglobulin-secreting cells (Mammalian Phenotype Ontology, MP_0008627)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008627
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Genes

3 gene mutations causing the decreased circulating interleukin-5 level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CARD11 caspase recruitment domain family, member 11
IL5 interleukin 5
NLRP3 NLR family, pyrin domain containing 3