decreased circulating interleukin-12b level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the amount in the blood of the p40 cytokine subunit that is a component of both interleukin-12 and interleukin-23 (Mammalian Phenotype Ontology, MP_0008648)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008648
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Genes

9 gene mutations causing the decreased circulating interleukin-12b level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL22 interleukin 22
IRF5 interferon regulatory factor 5
MYD88 myeloid differentiation primary response 88
NLRP3 NLR family, pyrin domain containing 3
PELI1 pellino E3 ubiquitin protein ligase 1
TICAM1 toll-like receptor adaptor molecule 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UNC93B1 unc-93 homolog B1 (C. elegans)