decreased chemically-elicited antinociception Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than the normal analgesic effect of chemical substances (Mammalian Phenotype Ontology, MP_0001982)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001982
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Genes

19 gene mutations causing the decreased chemically-elicited antinociception phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
BDKRB1 bradykinin receptor B1
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CHRM2 cholinergic receptor, muscarinic 2
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CNR1 cannabinoid receptor 1 (brain)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
IL6 interleukin 6
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
MGLL monoglyceride lipase
NTSR1 neurotensin receptor 1 (high affinity)
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
PDYN prodynorphin