decreased cerebral infarction size Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description decreased size of necrotic area of the cerebrum resulting from a sudden insufficiency of arterial or venous blood supply (Mammalian Phenotype Ontology, MP_0006058)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0006058
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Genes

29 gene mutations causing the decreased cerebral infarction size phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADORA2A adenosine A2a receptor
APOE apolipoprotein E
C3 complement component 3
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CX3CL1 chemokine (C-X3-C motif) ligand 1
DAPK1 death-associated protein kinase 1
EGR1 early growth response 1
F11 coagulation factor XI
F12 coagulation factor XII (Hageman factor)
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GPX3 glutathione peroxidase 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IL18 interleukin 18
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
NBEAL2 neurobeachin-like 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOX4 NADPH oxidase 4
OLFM1 olfactomedin 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAT plasminogen activator, tissue
PLD1 phospholipase D1, phosphatidylcholine-specific
PPIF peptidylprolyl isomerase F
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
STIM2 stromal interaction molecule 2
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)