decreased cellular sensitivity to oxidative stress Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced incidence of cell death or enhanced production of reactive oxygen species after exposure to a variety of stress conditions including ionizing radiation, exposure to xenobiotics, inflammation, and phagocytosis (Mammalian Phenotype Ontology, MP_0008413)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008413
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Genes

3 gene mutations causing the decreased cellular sensitivity to oxidative stress phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
PPIF peptidylprolyl isomerase F
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)