decreased cell migration Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced or slower movement of cells from one site to another, often occurring during developmental or chemotactic processes (Mammalian Phenotype Ontology, MP_0011805)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011805
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Genes

36 gene mutations causing the decreased cell migration phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARID5B AT rich interactive domain 5B (MRF1-like)
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
CD22 CD22 molecule
CLIC4 chloride intracellular channel 4
CYLD cylindromatosis (turban tumor syndrome)
DCBLD2 discoidin, CUB and LCCL domain containing 2
EGFR epidermal growth factor receptor
EHD1 EH-domain containing 1
FLNB filamin B, beta
FNDC3B fibronectin type III domain containing 3B
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
ILK integrin-linked kinase
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MRC2 mannose receptor, C type 2
MTSS1 metastasis suppressor 1
NCOA3 nuclear receptor coactivator 3
PALLD palladin, cytoskeletal associated protein
PECAM1 platelet/endothelial cell adhesion molecule 1
PLEC plectin
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PTK2 protein tyrosine kinase 2
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RHOB ras homolog family member B
S1PR1 sphingosine-1-phosphate receptor 1
SCHIP1 schwannomin interacting protein 1
SDC4 syndecan 4
SGPL1 sphingosine-1-phosphate lyase 1
SOX10 SRY (sex determining region Y)-box 10
SYNE2 spectrin repeat containing, nuclear envelope 2
TGS1 trimethylguanosine synthase 1
WDPCP WD repeat containing planar cell polarity effector
ZFAND5 zinc finger, AN1-type domain 5
ZYX zyxin