decreased bronchoconstrictive response Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the expected bronchoconstrictive response to provocation challenge with lipopolysaccharide, bradykinin, histamine or other antigen/allergen or agent, often measured by plethysmography (Mammalian Phenotype Ontology, MP_0012125)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0012125
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Genes

3 gene mutations causing the decreased bronchoconstrictive response phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CHRM2 cholinergic receptor, muscarinic 2
CHRM3 cholinergic receptor, muscarinic 3
MYH11 myosin, heavy chain 11, smooth muscle