decreased bone trabecula number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description decreased number of intersecting plates and spicules in cancellous bone which form a meshwork of intercommunicating spaces filled with blood vessels and marrow; in mature bone, the trabeculae are aligned in parallel with the lines of major compressive or tensile force (Mammalian Phenotype Ontology, MP_0010869)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010869
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Genes

40 gene mutations causing the decreased bone trabecula number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABHD5 abhydrolase domain containing 5
ADIPOQ adiponectin, C1Q and collagen domain containing
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHSY1 chondroitin sulfate synthase 1
CLDN18 claudin 18
CLEC2D C-type lectin domain family 2, member D
CNOT3 CCR4-NOT transcription complex, subunit 3
COL1A2 collagen, type I, alpha 2
COL2A1 collagen, type II, alpha 1
CTHRC1 collagen triple helix repeat containing 1
EIF4E3 eukaryotic translation initiation factor 4E family member 3
FAM73B family with sequence similarity 73, member B
FBLIM1 filamin binding LIM protein 1
FBN1 fibrillin 1
FIG4 FIG4 phosphoinositide 5-phosphatase
FZD9 frizzled class receptor 9
GALC galactosylceramidase
IL10 interleukin 10
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
JAK1 Janus kinase 1
LMNA lamin A/C
MCPH1 microcephalin 1
MGP matrix Gla protein
NACA nascent polypeptide-associated complex alpha subunit
NLRP3 NLR family, pyrin domain containing 3
NOV nephroblastoma overexpressed
PHF20 PHD finger protein 20
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
SH3BP2 SH3-domain binding protein 2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SUCO SUN domain containing ossification factor
TMEM119 transmembrane protein 119
TWSG1 twisted gastrulation BMP signaling modulator 1
WWOX WW domain containing oxidoreductase
XYLT1 xylosyltransferase I