decreased bone resorption Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced amount of degradation of the organic and inorganic phases of bone by absorption, usually by the abnormal function or number of osteoclasts (Mammalian Phenotype Ontology, MP_0004993)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004993
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Genes

24 gene mutations causing the decreased bone resorption phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AGER advanced glycosylation end product-specific receptor
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
CD47 CD47 molecule
CD68 CD68 molecule
CLCN7 chloride channel, voltage-sensitive 7
CSF1 colony stimulating factor 1 (macrophage)
ESRRA estrogen-related receptor alpha
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
GAB2 GRB2-associated binding protein 2
GPR65 G protein-coupled receptor 65
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IL20RA interleukin 20 receptor, alpha
LRP5 low density lipoprotein receptor-related protein 5
LRRK1 leucine-rich repeat kinase 1
PHEX phosphate regulating endopeptidase homolog, X-linked
SIGLEC15 sialic acid binding Ig-like lectin 15
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYK spleen tyrosine kinase
TMEM64 transmembrane protein 64
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TYROBP TYRO protein tyrosine kinase binding protein