decreased autoantibody level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced level of antibodies to self-antigens present in the sera (Mammalian Phenotype Ontology, MP_0003726)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003726
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Genes

8 gene mutations causing the decreased autoantibody level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AIRE autoimmune regulator
CD19 CD19 molecule
CORO1A coronin, actin binding protein, 1A
ICOS inducible T-cell co-stimulator
IFNG interferon, gamma
MERTK MER proto-oncogene, tyrosine kinase
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8