decreased airway responsiveness Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less easily provoked into bronchoconstriction during bronchial provocation testing (Mammalian Phenotype Ontology, MP_0002335)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002335
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Genes

22 gene mutations causing the decreased airway responsiveness phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADORA3 adenosine A3 receptor
C3AR1 complement component 3a receptor 1
CALCB calcitonin-related polypeptide beta
CARD11 caspase recruitment domain family, member 11
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung)
CXCR2 chemokine (C-X-C motif) receptor 2
IFNG interferon, gamma
IL10 interleukin 10
IL13RA1 interleukin 13 receptor, alpha 1
IL17RB interleukin 17 receptor B
IL33 interleukin 33
IL4 interleukin 4
IL5 interleukin 5
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LTB4R leukotriene B4 receptor
MINA MYC induced nuclear antigen
NGFR nerve growth factor receptor
PRKCQ protein kinase C, theta
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
TNFAIP6 tumor necrosis factor, alpha-induced protein 6