decreased aggression Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description when compared to controls, subjects exhibit less than the normal level of domineering, assault posture and/or hostile physical action (Mammalian Phenotype Ontology, MP_0005656)
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42 gene mutations causing the decreased aggression phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARX aristaless related homeobox
AVPR1B arginine vasopressin receptor 1B
BBS1 Bardet-Biedl syndrome 1
BBS2 Bardet-Biedl syndrome 2
BBS4 Bardet-Biedl syndrome 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DRD2 dopamine receptor D2
DST dystonin
EGR1 early growth response 1
EN2 engrailed homeobox 2
ESR1 estrogen receptor 1
FMR1 fragile X mental retardation 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GDI1 GDP dissociation inhibitor 1
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRN granulin
GTF2IRD1 GTF2I repeat domain containing 1
KIRREL3 kin of IRRE like 3 (Drosophila)
LAMA2 laminin, alpha 2
LSAMP limbic system-associated membrane protein
MAP6 microtubule-associated protein 6
MC5R melanocortin 5 receptor
MKKS McKusick-Kaufman syndrome
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NOS1 nitric oxide synthase 1 (neuronal)
OPHN1 oligophrenin 1
OXT oxytocin/neurophysin I prepropeptide
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGS2 regulator of G-protein signaling 2
RGS4 regulator of G-protein signaling 4
RORB RAR-related orphan receptor B
SYN3 synapsin III
TACR1 tachykinin receptor 1
TP73 tumor protein p73
TPGS1 tubulin polyglutamylase complex subunit 1
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TSN translin
ZIC2 Zic family member 2