decreased activation-induced b cell apoptosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description decreased frequency of B cell apoptosis that occurs upon engagement of either the B cell receptor or CD40, but not both; the engagement leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death (Mammalian Phenotype Ontology, MP_0010675)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010675
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Genes

3 gene mutations causing the decreased activation-induced b cell apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
OTUD7B OTU deubiquitinase 7B
PKN1 protein kinase N1
SPPL2A signal peptide peptidase like 2A