cytoplasmic pattern recognition receptor signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any series of molecular signals generated as a consequence of a cytoplasmic pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells. (Gene Ontology, GO_0002753)
External Link http://amigo.geneontology.org/amigo/term/GO:0002753
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Genes

33 genes participating in the cytoplasmic pattern recognition receptor signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
CARD9 caspase recruitment domain family, member 9
CASP8 caspase 8, apoptosis-related cysteine peptidase
CHUK conserved helix-loop-helix ubiquitous kinase
CYLD cylindromatosis (turban tumor syndrome)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
IFIH1 interferon induced with helicase C domain 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
ITCH itchy E3 ubiquitin protein ligase
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAVS mitochondrial antiviral signaling protein
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
OTULIN OTU deubiquitinase with linear linkage specificity
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RIPK2 receptor-interacting serine-threonine kinase 2
RPS27A ribosomal protein S27a
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2N ubiquitin-conjugating enzyme E2N
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