cytoplasmic mrna processing body Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. mRNA processing and binding proteins are localized to these foci. (Gene Ontology, GO_0000932)
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Genes

240 proteins co-occuring with the cytoplasmic mrna processing body cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 2.37147
DCP1A decapping mRNA 1A 2.28846
DCP2 decapping mRNA 2 2.27752
AGO2 argonaute RISC catalytic component 2 2.16832
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 2.00263
EDC3 enhancer of mRNA decapping 3 1.92299
LSM1 LSM1, U6 small nuclear RNA associated 1.90285
XRN1 5'-3' exoribonuclease 1 1.86831
TRIM5 tripartite motif containing 5 1.65092
AGO1 argonaute RISC catalytic component 1 1.59257
EIF4E eukaryotic translation initiation factor 4E 1.53274
TNRC6B trinucleotide repeat containing 6B 1.4921
EDC4 enhancer of mRNA decapping 4 1.47061
PATL1 protein associated with topoisomerase II homolog 1 (yeast) 1.44799
TSPO translocator protein (18kDa) 1.44799
PABPC1 poly(A) binding protein, cytoplasmic 1 1.41923
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 1.39127
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 1.35266
HEXA hexosaminidase A (alpha polypeptide) 1.33848
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 1.32762
TNRC6A trinucleotide repeat containing 6A 1.31573
BTBD2 BTB (POZ) domain containing 2 1.25075
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 1.23975
ZNF318 zinc finger protein 318 1.21325
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.20963
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 1.16594
BTBD1 BTB (POZ) domain containing 1 1.16491
ATXN2 ataxin 2 1.13625
MOV10 Mov10 RISC complex RNA helicase 1.13318
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 1.13012
SMG6 SMG6 nonsense mediated mRNA decay factor 1.12501
ELAVL1 ELAV like RNA binding protein 1 1.11225
TDRD9 tudor domain containing 9 1.10562
DICER1 dicer 1, ribonuclease type III 1.09035
MEX3B mex-3 RNA binding family member B 1.05488
CNOT6L CCR4-NOT transcription complex, subunit 6-like 1.05236
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 1.03729
SAMD4A sterile alpha motif domain containing 4A 1.03529
PNRC2 proline-rich nuclear receptor coactivator 2 1.02879
TNRC6C trinucleotide repeat containing 6C 1.01784
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.01288
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.995142
TDRD1 tudor domain containing 1 0.983419
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.958789
DCP1B decapping mRNA 1B 0.954005
STAU1 staufen double-stranded RNA binding protein 1 0.911579
PIWIL1 piwi-like RNA-mediated gene silencing 1 0.909251
CNOT1 CCR4-NOT transcription complex, subunit 1 0.898109
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase 0.880555
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 0.879633
DIS3L DIS3 like exosome 3'-5' exoribonuclease 0.878251
NANOS2 nanos homolog 2 (Drosophila) 0.876409
TRIM65 tripartite motif containing 65 0.870885
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 0.857095
HEXB hexosaminidase B (beta polypeptide) 0.85388
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.848828
PIWIL4 piwi-like RNA-mediated gene silencing 4 0.831843
MEX3D mex-3 RNA binding family member D 0.823582
CASC3 cancer susceptibility candidate 3 0.807524
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 0.800187
SMG5 SMG5 nonsense mediated mRNA decay factor 0.770451
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.759069
GEMIN5 gem (nuclear organelle) associated protein 5 0.74322
CAPRIN1 cell cycle associated protein 1 0.740064
ATXN2L ataxin 2-like 0.73287
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 0.731076
PARN poly(A)-specific ribonuclease 0.73018
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 0.700423
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 0.698663
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.693832
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.692078
CNOT6 CCR4-NOT transcription complex, subunit 6 0.687264
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 0.683335
ZAR1L zygote arrest 1-like 0.680284
TRIM21 tripartite motif containing 21 0.656033
DCPS decapping enzyme, scavenger 0.638861
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 0.635013
IFI44L interferon-induced protein 44-like 0.624355
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.620104
PCBP2 poly(rC) binding protein 2 0.612895
EIF4A3 eukaryotic translation initiation factor 4A3 0.602752
CELF1 CUGBP, Elav-like family member 1 0.590553
YBX1 Y box binding protein 1 0.583849
TPRKB TP53RK binding protein 0.583431
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.580086
CDA cytidine deaminase 0.577164
NGDN neuroguidin, EIF4E binding protein 0.565923
SRSF3 serine/arginine-rich splicing factor 3 0.563017
PRR5L proline rich 5 like 0.5568
LSM12 LSM12 homolog (S. cerevisiae) 0.555973
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.546885
ERMAP erythroblast membrane-associated protein (Scianna blood group) 0.540294
CNOT7 CCR4-NOT transcription complex, subunit 7 0.537827
EIF3E eukaryotic translation initiation factor 3, subunit E 0.527569
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.517348
MEX3C mex-3 RNA binding family member C 0.512047
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.507977
EIF4E2 eukaryotic translation initiation factor 4E family member 2 0.50635
DND1 DND microRNA-mediated repression inhibitor 1 0.492966
TBC1D24 TBC1 domain family, member 24 0.490539
LARP1 La ribonucleoprotein domain family, member 1 0.489731
DEF6 differentially expressed in FDCP 6 homolog (mouse) 0.488923
NANOS3 nanos homolog 3 (Drosophila) 0.488519
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.482467
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.482467
FUS FUS RNA binding protein 0.475223
DGCR8 DGCR8 microprocessor complex subunit 0.472412
CUTA cutA divalent cation tolerance homolog (E. coli) 0.472011
WDFY1 WD repeat and FYVE domain containing 1 0.466399
FHL1 four and a half LIM domains 1 0.465998
TSKS testis-specific serine kinase substrate 0.465998
TDRD6 tudor domain containing 6 0.453621
CIRBP cold inducible RNA binding protein 0.452427
VCX3A variable charge, X-linked 3A 0.442896
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 0.440916
ZNF692 zinc finger protein 692 0.439728
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.429859
CBS cystathionine-beta-synthase 0.428284
ARHGAP8 Rho GTPase activating protein 8 0.428284
PUM1 pumilio RNA-binding family member 1 0.426318
CNOT3 CCR4-NOT transcription complex, subunit 3 0.425531
RPL28 ribosomal protein L28 0.424353
SH3GL3 SH3-domain GRB2-like 3 0.414555
PRMT1 protein arginine methyltransferase 1 0.409869
KHSRP KH-type splicing regulatory protein 0.408699
CNOT8 CCR4-NOT transcription complex, subunit 8 0.407919
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.405193
MAGOHB mago-nashi homolog B (Drosophila) 0.403637
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 0.398199
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.388523
MVK mevalonate kinase 0.388137
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 0.381584
CNTN4 contactin 4 0.381584
SMN2 survival of motor neuron 2, centromeric 0.381199
MYOT myotilin 0.381199
ZBP1 Z-DNA binding protein 1 0.379276
GOLGB1 golgin B1 0.377354
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 0.376586
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 0.371982
AHRR aryl-hydrocarbon receptor repressor 0.370833
SRP19 signal recognition particle 19kDa 0.37045
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 0.37045
DPPA4 developmental pluripotency associated 4 0.358609
LIMD1 LIM domains containing 1 0.351382
MIF4GD MIF4G domain containing 0.348725
PRMT2 protein arginine methyltransferase 2 0.338884
SMN1 survival of motor neuron 1, telomeric 0.332095
SAE1 SUMO1 activating enzyme subunit 1 0.329837
PIWIL2 piwi-like RNA-mediated gene silencing 2 0.327956
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.326829
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.325702
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 0.32345
MAEL maelstrom spermatogenic transposon silencer 0.322325
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.321201
IPO8 importin 8 0.320826
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.320077
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.318579
MIR25 microRNA 25 0.316334
ZC3H12D zinc finger CCCH-type containing 12D 0.313718
CERKL ceramide kinase-like 0.310358
PUM2 pumilio RNA-binding family member 2 0.305888
ZAR1 zygote arrest 1 0.305143
YBX2 Y box binding protein 2 0.304399
GLB1 galactosidase, beta 1 0.302912
MIR222 microRNA 222 0.301797
TDRD7 tudor domain containing 7 0.301797
SH2D3C SH2 domain containing 3C 0.300682
YIPF7 Yip1 domain family, member 7 0.296601
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.29586
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 0.292157
QPRT quinolinate phosphoribosyltransferase 0.292157
DAZAP2 DAZ associated protein 2 0.291417
RBM8A RNA binding motif protein 8A 0.290308
CGN cingulin 0.289938
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 0.285507
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.285507
MIR10B microRNA 10b 0.282926
WDR62 WD repeat domain 62 0.278141
SPRED1 sprouty-related, EVH1 domain containing 1 0.277774
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.271533
TARDBP TAR DNA binding protein 0.269701
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 0.268969
HSPA4 heat shock 70kDa protein 4 0.268237
KRAS Kirsten rat sarcoma viral oncogene homolog 0.267505
DPPA2 developmental pluripotency associated 2 0.266042
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.265677
XPO1 exportin 1 0.26239
RRM2 ribonucleotide reductase M2 0.262025
CCNF cyclin F 0.262025
STK38 serine/threonine kinase 38 0.260566
PRMT5 protein arginine methyltransferase 5 0.254743
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa 0.250389
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.246046
KLC3 kinesin light chain 3 0.24424
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.243879
PAPD4 PAP associated domain containing 4 0.239557
LAMP2 lysosomal-associated membrane protein 2 0.238837
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.231672
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 0.229532
LHCGR luteinizing hormone/choriogonadotropin receptor 0.228819
RRM1 ribonucleotide reductase M1 0.227752
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.224913
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.224204
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 0.222436
EIF3F eukaryotic translation initiation factor 3, subunit F 0.222083
PITX3 paired-like homeodomain 3 0.220321
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 0.217861
WDR77 WD repeat domain 77 0.21646
RPS20 ribosomal protein S20 0.211587
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.211587
DHPS deoxyhypusine synthase 0.209513
EIF3C eukaryotic translation initiation factor 3, subunit C 0.207108
CNOT2 CCR4-NOT transcription complex, subunit 2 0.205399
ACPP acid phosphatase, prostate 0.204039
ZFP36 ZFP36 ring finger protein 0.203022
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.203022
WTIP Wilms tumor 1 interacting protein 0.201672
SEC31A SEC31 homolog A (S. cerevisiae) 0.197993
CUL4B cullin 4B 0.197993
ALK anaplastic lymphoma receptor tyrosine kinase 0.195681
VCP valosin containing protein 0.195025
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 0.193394
PLIN4 perilipin 4 0.191777
TTN titin 0.189857
PDE5A phosphodiesterase 5A, cGMP-specific 0.189539
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.181227
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.180045
MYO5C myosin VC 0.178877
DLK1 delta-like 1 homolog (Drosophila) 0.178299
HPS4 Hermansky-Pudlak syndrome 4 0.176587
TRIM32 tripartite motif containing 32 0.174087
PARK2 parkin RBR E3 ubiquitin protein ligase 0.174087
RPL9 ribosomal protein L9 0.173543
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 0.168598
RAE1 ribonucleic acid export 1 0.167366
DROSHA drosha, ribonuclease type III 0.166167
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.164089
IFIH1 interferon induced with helicase C domain 1 0.164089
RPS3 ribosomal protein S3 0.160863
POMP proteasome maturation protein 0.157218