cyclin d2-cdk4 complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex consisting of cyclin D2 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. (Gene Ontology, GO_0097129)
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18 proteins co-occuring with the cyclin d2-cdk4 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CCND2 cyclin D2 1.31196
CDK2 cyclin-dependent kinase 2 1.26551
CDK6 cyclin-dependent kinase 6 1.17824
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.04934
CDK4 cyclin-dependent kinase 4 0.918579
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.886089
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.716346
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.554318
CDK7 cyclin-dependent kinase 7 0.524704
CCND3 cyclin D3 0.443689
APC adenomatous polyposis coli 0.391615
TGFB1 transforming growth factor, beta 1 0.300311
RB1 retinoblastoma 1 0.216111
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.208825
FYN FYN proto-oncogene, Src family tyrosine kinase 0.18796
CD40LG CD40 ligand 0.186708
IL10 interleukin 10 0.183328
LCK LCK proto-oncogene, Src family tyrosine kinase 0.172201