cyclin d1-cdk4 complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex consisting of cyclin D1 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. (Gene Ontology, GO_0097128)
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38 proteins co-occuring with the cyclin d1-cdk4 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CDK4 cyclin-dependent kinase 4 2.34482
CCND1 cyclin D1 2.0685
CDK2 cyclin-dependent kinase 2 1.92021
CDK6 cyclin-dependent kinase 6 1.51751
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.44516
CDKN2A cyclin-dependent kinase inhibitor 2A 1.23505
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.23452
CCND3 cyclin D3 1.06347
RB1 retinoblastoma 1 1.02131
CDK7 cyclin-dependent kinase 7 0.863068
TRIM3 tripartite motif containing 3 0.695148
AK6 adenylate kinase 6 0.690326
SERTAD1 SERTA domain containing 1 0.65001
E2F4 E2F transcription factor 4, p107/p130-binding 0.60444
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.585523
E2F1 E2F transcription factor 1 0.535361
HRAS Harvey rat sarcoma viral oncogene homolog 0.512455
PCNA proliferating cell nuclear antigen 0.498636
TP53 tumor protein p53 0.498636
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.416511
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.390841
CDC25A cell division cycle 25A 0.385436
CCNE2 cyclin E2 0.384665
CCND2 cyclin D2 0.358609
CIRBP cold inducible RNA binding protein 0.357086
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.326829
CCNH cyclin H 0.294007
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.289199
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.277774
KAT2A K(lysine) acetyltransferase 2A 0.2719
GSK3B glycogen synthase kinase 3 beta 0.266774
CCNB1 cyclin B1 0.239197
CCNE1 cyclin E1 0.230601
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.180634
CDK1 cyclin-dependent kinase 1 0.180045
PDHX pyruvate dehydrogenase complex, component X 0.176587
ERBB2 erb-b2 receptor tyrosine kinase 2 0.165697
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.156863