cyclin binding Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis. (Gene Ontology, GO_0030332)
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19 genes performing the cyclin binding molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
CDK1 cyclin-dependent kinase 1
CDK12 cyclin-dependent kinase 12
CDK13 cyclin-dependent kinase 13
CDK14 cyclin-dependent kinase 14
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CUL3 cullin 3
FBXO31 F-box protein 31
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
HDAC3 histone deacetylase 3
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1
INSM1 insulinoma-associated 1
MDFIC MyoD family inhibitor domain containing
POLN polymerase (DNA directed) nu
PTCH1 patched 1
USP2 ubiquitin specific peptidase 2