cyanocobalamin-4572 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the cyanocobalamin-4572 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADRA1D adrenoceptor alpha 1D
ADRBK2 adrenergic, beta, receptor kinase 2
AGBL2 ATP/GTP binding protein-like 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AK5 adenylate kinase 5
ARHGAP28 Rho GTPase activating protein 28
ASTN2 astrotactin 2
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
C11ORF16 chromosome 11 open reading frame 16
C2ORF27A chromosome 2 open reading frame 27A
C9ORF156 chromosome 9 open reading frame 156
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CGA glycoprotein hormones, alpha polypeptide
CNR2 cannabinoid receptor 2 (macrophage)
COL10A1 collagen, type X, alpha 1
CREM cAMP responsive element modulator
CRISP2 cysteine-rich secretory protein 2
CRP C-reactive protein, pentraxin-related
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DCSTAMP dendrocyte expressed seven transmembrane protein
DTNA dystrobrevin, alpha
EGR2 early growth response 2
ESRRG estrogen-related receptor gamma
EYA3 EYA transcriptional coactivator and phosphatase 3
FABP3 fatty acid binding protein 3, muscle and heart
FOXD2 forkhead box D2
GAB1 GRB2-associated binding protein 1
GIF gastric intrinsic factor (vitamin B synthesis)
GRM8 glutamate receptor, metabotropic 8
GSPT1 G1 to S phase transition 1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HIST1H3I histone cluster 1, H3i
HNF4A hepatocyte nuclear factor 4, alpha
HRASLS2 HRAS-like suppressor 2
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IL1R1 interleukin 1 receptor, type I
ING2 inhibitor of growth family, member 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM8 lysine (K)-specific demethylase 8
KHK ketohexokinase (fructokinase)
KIAA0368 KIAA0368
LAX1 lymphocyte transmembrane adaptor 1
LMNA lamin A/C
LRRN3 leucine rich repeat neuronal 3
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MBD2 methyl-CpG binding domain protein 2
MFAP3L microfibrillar-associated protein 3-like
MPZ myelin protein zero
MUC2 mucin 2, oligomeric mucus/gel-forming
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NIPAL2 NIPA-like domain containing 2
NPR1 natriuretic peptide receptor 1
OR10H3 olfactory receptor, family 10, subfamily H, member 3
PCDHB3 protocadherin beta 3
PCDHGA11 protocadherin gamma subfamily A, 11
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDLIM3 PDZ and LIM domain 3
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRDM14 PR domain containing 14
PRKCDBP protein kinase C, delta binding protein
PSD4 pleckstrin and Sec7 domain containing 4
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RABGAP1L RAB GTPase activating protein 1-like
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RHCE Rh blood group, CcEe antigens
RIN3 Ras and Rab interactor 3
RPL10L ribosomal protein L10-like
SARM1 sterile alpha and TIR motif containing 1
SEMG2 semenogelin II
SERHL2 serine hydrolase-like 2
SLC17A4 solute carrier family 17, member 4
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SOGA1 suppressor of glucose, autophagy associated 1
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STOML1 stomatin (EPB72)-like 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TMPRSS2 transmembrane protease, serine 2
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TRIM3 tripartite motif containing 3
UPK1B uroplakin 1B
VCL vinculin
WFDC2 WAP four-disulfide core domain 2
WNT8B wingless-type MMTV integration site family, member 8B
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF268 zinc finger protein 268
ZNF44 zinc finger protein 44

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACBD4 acyl-CoA binding domain containing 4
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANP32A-IT1 ANP32A intronic transcript 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BTF3P12 basic transcription factor 3 pseudogene 12
C10ORF88 chromosome 10 open reading frame 88
C17ORF80 chromosome 17 open reading frame 80
C1R complement component 1, r subcomponent
C3 complement component 3
C9ORF40 chromosome 9 open reading frame 40
CA11 carbonic anhydrase XI
CCNJL cyclin J-like
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CES3 carboxylesterase 3
CFAP69 cilia and flagella associated protein 69
CHD8 chromodomain helicase DNA binding protein 8
CLDN14 claudin 14
CUL9 cullin 9
DENND4A DENN/MADD domain containing 4A
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DTX2 deltex 2, E3 ubiquitin ligase
EN2 engrailed homeobox 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERO1LB ERO1-like beta (S. cerevisiae)
FAM118A family with sequence similarity 118, member A
FANCC Fanconi anemia, complementation group C
FCMR Fc fragment of IgM receptor
FPGS folylpolyglutamate synthase
GMEB1 glucocorticoid modulatory element binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GREB1L growth regulation by estrogen in breast cancer-like
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HCFC2 host cell factor C2
HPSE heparanase
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFI44L interferon-induced protein 44-like
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGSF3 immunoglobulin superfamily, member 3
IL17RB interleukin 17 receptor B
IL7R interleukin 7 receptor
INCENP inner centromere protein antigens 135/155kDa
JUNB jun B proto-oncogene
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCTD7 potassium channel tetramerization domain containing 7
KIAA1107 KIAA1107
LOC730101 uncharacterized LOC730101
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRRC37A3 leucine rich repeat containing 37, member A3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MXRA8 matrix-remodelling associated 8
MYBBP1A MYB binding protein (P160) 1a
NPIPB3 nuclear pore complex interacting protein family, member B3
NUPR1 nuclear protein, transcriptional regulator, 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSMR oncostatin M receptor
PAIP2B poly(A) binding protein interacting protein 2B
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDZD2 PDZ domain containing 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POR P450 (cytochrome) oxidoreductase
PRKX protein kinase, X-linked
PRMT7 protein arginine methyltransferase 7
PRPH peripherin
PTDSS2 phosphatidylserine synthase 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB4B RAB4B, member RAS oncogene family
RHOBTB2 Rho-related BTB domain containing 2
RIN1 Ras and Rab interactor 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF31 ring finger protein 31
RPL23AP32 ribosomal protein L23a pseudogene 32
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCML2 sex comb on midleg-like 2 (Drosophila)
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SHPK sedoheptulokinase
SLITRK5 SLIT and NTRK-like family, member 5
SPRYD7 SPRY domain containing 7
SYT17 synaptotagmin XVII
TBC1D17 TBC1 domain family, member 17
TMEM2 transmembrane protein 2
TNRC6B trinucleotide repeat containing 6B
TRIM21 tripartite motif containing 21
TUBA3C tubulin, alpha 3c
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP18 ubiquitin specific peptidase 18
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VN1R1 vomeronasal 1 receptor 1
WNT7A wingless-type MMTV integration site family, member 7A
ZBTB22 zinc finger and BTB domain containing 22
ZNF215 zinc finger protein 215
ZNF747 zinc finger protein 747
ZNF768 zinc finger protein 768