crohn disease; crohn's disease Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group immune (Genetic Association Database)
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Genes

105 genes associated with the disease crohn disease; crohn's disease in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
AMIGO3 adhesion molecule with Ig-like domain 3
AMT aminomethyltransferase
APEH acylaminoacyl-peptide hydrolase
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATXN2L ataxin 2-like
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BCL3 B-cell CLL/lymphoma 3
BSN bassoon presynaptic cytomatrix protein
C5ORF56 chromosome 5 open reading frame 56
CADM1 cell adhesion molecule 1
CARD8 caspase recruitment domain family, member 8
CCL2 chemokine (C-C motif) ligand 2
CCL7 chemokine (C-C motif) ligand 7
CCNY cyclin Y
CD14 CD14 molecule
CDHR4 cadherin-related family member 4
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
COX11 COX11 cytochrome c oxidase copper chaperone
CPEB4 cytoplasmic polyadenylation element binding protein 4
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DENND1B DENN/MADD domain containing 1B
DLG5 discs, large homolog 5 (Drosophila)
DNAH12 dynein, axonemal, heavy chain 12
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK3 dedicator of cytokinesis 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERAP2 endoplasmic reticulum aminopeptidase 2
EXOC2 exocyst complex component 2
FAF1 Fas (TNFRSF6) associated factor 1
FUT2 fucosyltransferase 2 (secretor status included)
GMPPB GDP-mannose pyrophosphorylase B
GPC5 glypican 5
GPX1 glutathione peroxidase 1
GSDMB gasdermin B
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HORMAD2 HORMA domain containing 2
IBD5 inflammatory bowel disease 5
IL10 interleukin 10
IL23R interleukin 23 receptor
IL2RA interleukin 2 receptor, alpha
IP6K1 inositol hexakisphosphate kinase 1
IRGM immunity-related GTPase family, M
ITLN1 intelectin 1 (galactofuranose binding)
LACC1 laccase (multicopper oxidoreductase) domain containing 1
LTA lymphotoxin alpha
LYRM4 LYR motif containing 4
MBL2 mannose-binding lectin (protein C) 2, soluble
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMD2 monocyte to macrophage differentiation-associated 2
MST1 macrophage stimulating 1
NICN1 nicolin 1
NKX2-3 NK2 homeobox 3
NLRP1 NLR family, pyrin domain containing 1
NLRP10 NLR family, pyrin domain containing 10
NLRP11 NLR family, pyrin domain containing 11
NLRP12 NLR family, pyrin domain containing 12
NLRP13 NLR family, pyrin domain containing 13
NLRP14 NLR family, pyrin domain containing 14
NLRP2 NLR family, pyrin domain containing 2
NLRP3 NLR family, pyrin domain containing 3
NLRP4 NLR family, pyrin domain containing 4
NLRP5 NLR family, pyrin domain containing 5
NLRP6 NLR family, pyrin domain containing 6
NLRP7 NLR family, pyrin domain containing 7
NLRP8 NLR family, pyrin domain containing 8
NLRP9 NLR family, pyrin domain containing 9
NOD2 nucleotide-binding oligomerization domain containing 2
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
POU2F1 POU class 2 homeobox 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RHOA ras homolog family member A
RMI2 RecQ mediated genome instability 2
RNASET2 ribonuclease T2
RNF123 ring finger protein 123
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A23 solute carrier family 22, member 23
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SMAD3 SMAD family member 3
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STX8 syntaxin 8
SURF1 surfeit 1
SYMPK symplekin
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAGAP T-cell activation RhoGTPase activating protein
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TP53 tumor protein p53
TRAIP TRAF interacting protein
TYK2 tyrosine kinase 2
UBA7 ubiquitin-like modifier activating enzyme 7
UBE2L3 ubiquitin-conjugating enzyme E2L 3
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF266 zinc finger protein 266
ZNF365 zinc finger protein 365