crohn's disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An intestinal disease that involves inflammation located_in intestine. (Human Disease Ontology, DOID_8778)
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Genes

649 genes co-occuring with the disease crohn's disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
NOD2 nucleotide-binding oligomerization domain containing 2 3.33808
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 2.58446
IRGM immunity-related GTPase family, M 2.22232
TNF tumor necrosis factor 2.11974
CRP C-reactive protein, pentraxin-related 2.06533
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.98575
DLG5 discs, large homolog 5 (Drosophila) 1.93608
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.82821
NOD1 nucleotide-binding oligomerization domain containing 1 1.80878
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.75596
TPMT thiopurine S-methyltransferase 1.75187
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 1.74915
NKX2-3 NK2 homeobox 3 1.7396
CD4 CD4 molecule 1.68317
CD79A CD79a molecule, immunoglobulin-associated alpha 1.6651
IL1B interleukin 1, beta 1.6507
IL10 interleukin 10 1.62425
IL23R interleukin 23 receptor 1.6086
ALB albumin 1.5943
TLR4 toll-like receptor 4 1.56889
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.53172
LTF lactotransferrin 1.50403
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 1.37076
DEFA5 defensin, alpha 5, Paneth cell-specific 1.36248
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 1.33327
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.32148
LYZ lysozyme 1.31493
RIPK2 receptor-interacting serine-threonine kinase 2 1.31406
IL6 interleukin 6 1.27344
MPO myeloperoxidase 1.26516
ITM2B integral membrane protein 2B 1.21175
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.19316
ICAM1 intercellular adhesion molecule 1 1.19273
DEFA6 defensin, alpha 6, Paneth cell-specific 1.191
TLR2 toll-like receptor 2 1.18539
FAM92B family with sequence similarity 92, member B 1.1541
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.1439
TLR5 toll-like receptor 5 1.13205
CXCL8 chemokine (C-X-C motif) ligand 8 1.12656
TGFB1 transforming growth factor, beta 1 1.10426
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 1.10343
CD68 CD68 molecule 1.09839
IL1RN interleukin 1 receptor antagonist 1.09629
GP2 glycoprotein 2 (zymogen granule membrane) 1.09629
CCL25 chemokine (C-C motif) ligand 25 1.07572
NLRP3 NLR family, pyrin domain containing 3 1.07278
HPS1 Hermansky-Pudlak syndrome 1 1.06144
NCF4 neutrophil cytosolic factor 4, 40kDa 1.05639
CARD8 caspase recruitment domain family, member 8 1.04504
FOXP3 forkhead box P3 1.04504
S100A12 S100 calcium binding protein A12 1.04251
ICOSLG inducible T-cell co-stimulator ligand 1.03788
CCR6 chemokine (C-C motif) receptor 6 1.03367
IL18 interleukin 18 1.02608
OCLN occludin 1.02187
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 1.02102
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 1.01723
RNF186 ring finger protein 186 1.01427
IL17A interleukin 17A 1.01174
LCT lactase 1.00288
PRTN3 proteinase 3 1.00203
ALPPL2 alkaline phosphatase, placental-like 2 0.999503
LACC1 laccase (multicopper oxidoreductase) domain containing 1 0.999503
ALPP alkaline phosphatase, placental 0.998658
ALPL alkaline phosphatase, liver/bone/kidney 0.998236
CCL20 chemokine (C-C motif) ligand 20 0.994439
IL2RA interleukin 2 receptor, alpha 0.993596
IL2 interleukin 2 0.992752
MBL2 mannose-binding lectin (protein C) 2, soluble 0.987693
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.97212
NELFCD negative elongation factor complex member C/D 0.97128
MUC19 mucin 19, oligomeric 0.960797
HPS4 Hermansky-Pudlak syndrome 4 0.944938
CCNY cyclin Y 0.944106
IGF1 insulin-like growth factor 1 (somatomedin C) 0.927932
HPS3 Hermansky-Pudlak syndrome 3 0.925039
IL10RA interleukin 10 receptor, alpha 0.924626
TBX21 T-box 21 0.924213
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.918024
C1ORF106 chromosome 1 open reading frame 106 0.917199
CARD9 caspase recruitment domain family, member 9 0.915139
BGLAP bone gamma-carboxyglutamate (gla) protein 0.909376
STAT4 signal transducer and activator of transcription 4 0.897461
ZNF365 zinc finger protein 365 0.896641
BPI bactericidal/permeability-increasing protein 0.88516
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.882292
IL23A interleukin 23, alpha subunit p19 0.880653
CA2 carbonic anhydrase II 0.8741
CXCR3 chemokine (C-X-C motif) receptor 3 0.860999
MYO9B myosin IXB 0.859771
HLA-C major histocompatibility complex, class I, C 0.849536
VIP vasoactive intestinal peptide 0.84544
MRAP melanocortin 2 receptor accessory protein 0.842982
CD40 CD40 molecule, TNF receptor superfamily member 5 0.842982
CCR9 chemokine (C-C motif) receptor 9 0.840115
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.831099
TF transferrin 0.827409
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.823718
TAC1 tachykinin, precursor 1 0.822488
HPS5 Hermansky-Pudlak syndrome 5 0.822077
TFF2 trefoil factor 2 0.822077
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 0.821667
TTR transthyretin 0.821257
FUT2 fucosyltransferase 2 (secretor status included) 0.820847
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.820437
IL22 interleukin 22 0.818385
PTPRD protein tyrosine phosphatase, receptor type, D 0.816745
IL18RAP interleukin 18 receptor accessory protein 0.81018
MUC2 mucin 2, oligomeric mucus/gel-forming 0.808949
CARD17 caspase recruitment domain family, member 17 0.807718
S100A9 S100 calcium binding protein A9 0.807718
CTSG cathepsin G 0.793771
CD80 CD80 molecule 0.792541
CUZD1 CUB and zona pellucida-like domains 1 0.785574
FKBP4 FK506 binding protein 4, 59kDa 0.778613
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.776977
CD86 CD86 molecule 0.767576
DEFB4A defensin, beta 4A 0.766759
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.761862
TAGAP T-cell activation RhoGTPase activating protein 0.757786
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.757378
TLR9 toll-like receptor 9 0.751271
MEFV Mediterranean fever 0.746798
LRRK2 leucine-rich repeat kinase 2 0.74436
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.739894
ATN1 atrophin 1 0.735433
ICAM3 intercellular adhesion molecule 3 0.735027
CXCL10 chemokine (C-X-C motif) ligand 10 0.728952
CD209 CD209 molecule 0.728547
IL32 interleukin 32 0.727738
MYLK3 myosin light chain kinase 3 0.724098
IL21 interleukin 21 0.721673
HP haptoglobin 0.718039
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.717232
HPR haptoglobin-related protein 0.711587
MYLK myosin light chain kinase 0.709975
A1BG alpha-1-B glycoprotein 0.708364
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.707961
TIMP1 TIMP metallopeptidase inhibitor 1 0.706351
F5 coagulation factor V (proaccelerin, labile factor) 0.705547
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.704742
CSN1S1 casein alpha s1 0.701526
FRMPD2 FERM and PDZ domain containing 2 0.700722
HEATR3 HEAT repeat containing 3 0.700722
SMAD7 SMAD family member 7 0.699517
JAK2 Janus kinase 2 0.699116
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.697911
AQP8 aquaporin 8 0.693499
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.691896
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 0.691495
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.688291
IL6R interleukin 6 receptor 0.687091
BTNL2 butyrophilin-like 2 0.685891
CD40LG CD40 ligand 0.685491
SELL selectin L 0.681495
IL12B interleukin 12B 0.680697
TMEM183A transmembrane protein 183A 0.679499
ARL4A ADP-ribosylation factor-like 4A 0.679499
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.678302
LCA10 lung carcinoma-associated 10 0.677903
NPS neuropeptide S 0.677504
ATG2A autophagy related 2A 0.677105
IFNG interferon, gamma 0.674713
IL18R1 interleukin 18 receptor 1 0.671925
ECM1 extracellular matrix protein 1 0.670333
MMP3 matrix metallopeptidase 3 0.669936
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.66199
ERAP2 endoplasmic reticulum aminopeptidase 2 0.658818
CD83 CD83 molecule 0.658026
MST1 macrophage stimulating 1 0.65565
CD19 CD19 molecule 0.65565
LTA lymphotoxin alpha 0.650903
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.647348
IL13 interleukin 13 0.646165
OTUD3 OTU deubiquitinase 3 0.64577
IL4 interleukin 4 0.64577
OR5V1 olfactory receptor, family 5, subfamily V, member 1 0.64577
ABHD3 abhydrolase domain containing 3 0.64577
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) 0.64577
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.643797
DMBT1 deleted in malignant brain tumors 1 0.643009
ATG4A autophagy related 4A, cysteine peptidase 0.642615
TRBJ2-5 T cell receptor beta joining 2-5 0.639463
IL11 interleukin 11 0.638676
ACD adrenocortical dysplasia homolog (mouse) 0.638282
VCAM1 vascular cell adhesion molecule 1 0.637495
XBP1 X-box binding protein 1 0.636315
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.635921
TJP1 tight junction protein 1 0.632777
STAT1 signal transducer and activator of transcription 1, 91kDa 0.631205
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 0.631205
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.628457
PLA2G1B phospholipase A2, group IB (pancreas) 0.623359
EBI3 Epstein-Barr virus induced 3 0.622575
ITLN1 intelectin 1 (galactofuranose binding) 0.622183
ATG5 autophagy related 5 0.620226
TPM1 tropomyosin 1 (alpha) 0.618268
ELANE elastase, neutrophil expressed 0.615529
NLRP1 NLR family, pyrin domain containing 1 0.614356
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.613965
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.611229
TLR6 toll-like receptor 6 0.603811
HNF4G hepatocyte nuclear factor 4, gamma 0.59952
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.59913
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.598351
CCL2 chemokine (C-C motif) ligand 2 0.592506
YDJC YdjC homolog (bacterial) 0.591337
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 0.588222
DEFB1 defensin, beta 1 0.587054
MYD88 myeloid differentiation primary response 88 0.586276
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.583941
CD276 CD276 molecule 0.582384
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.580439
ADSL adenylosuccinate lyase 0.58005
LEP leptin 0.58005
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.579661
REG3A regenerating islet-derived 3 alpha 0.577327
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.576939
SAA1 serum amyloid A1 0.575383
FTH1 ferritin, heavy polypeptide 1 0.573439
FTL ferritin, light polypeptide 0.573439
IL18BP interleukin 18 binding protein 0.569163
SAA2 serum amyloid A2 0.567997
CXCL9 chemokine (C-X-C motif) ligand 9 0.566443
FASLG Fas ligand (TNF superfamily, member 6) 0.566443
ALPI alkaline phosphatase, intestinal 0.565277
TREM1 triggering receptor expressed on myeloid cells 1 0.5645
TFRC transferrin receptor 0.561781
F13A1 coagulation factor XIII, A1 polypeptide 0.561004
AQP10 aquaporin 10 0.557509
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.55712
LBP lipopolysaccharide binding protein 0.555568
TGFB2 transforming growth factor, beta 2 0.55518
CCR2 chemokine (C-C motif) receptor 2 0.550911
PRDM1 PR domain containing 1, with ZNF domain 0.550134
GCG glucagon 0.549747
HLA-B major histocompatibility complex, class I, B 0.548971
PGM2L1 phosphoglucomutase 2-like 1 0.548195
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.548195
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13 0.547032
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 0.547032
CALCOCO2 calcium binding and coiled-coil domain 2 0.546256
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.54393
CTGF connective tissue growth factor 0.543155
SOCS3 suppressor of cytokine signaling 3 0.542767
MICA MHC class I polypeptide-related sequence A 0.541992
F2 coagulation factor II (thrombin) 0.541605
REG1B regenerating islet-derived 1 beta 0.539667
CXCL11 chemokine (C-X-C motif) ligand 11 0.537731
TACR1 tachykinin receptor 1 0.535409
CLDN1 claudin 1 0.534248
TLR1 toll-like receptor 1 0.532314
TFF3 trefoil factor 3 (intestinal) 0.529994
WBP4 WW domain binding protein 4 0.529608
LCN2 lipocalin 2 0.529222
IDO1 indoleamine 2,3-dioxygenase 1 0.52536
IL1A interleukin 1, alpha 0.523045
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.522659
DEFA3 defensin, alpha 3, neutrophil-specific 0.519961
CLDN4 claudin 4 0.519961
ADAD1 adenosine deaminase domain containing 1 (testis-specific) 0.516879
DEFB104B defensin, beta 104B 0.516494
PPARG peroxisome proliferator-activated receptor gamma 0.515725
ZSCAN9 zinc finger and SCAN domain containing 9 0.512648
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 0.512648
FNBP1L formin binding protein 1-like 0.511496
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.509192
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.508808
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 0.504973
CD1C CD1c molecule 0.499997
IL12RB2 interleukin 12 receptor, beta 2 0.499997
MUC3A mucin 3A, cell surface associated 0.498849
DEF8 differentially expressed in FDCP 8 homolog (mouse) 0.497703
PSKH1 protein serine kinase H1 0.496939
TRAIP TRAF interacting protein 0.496939
HLA-A major histocompatibility complex, class I, A 0.496557
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.494648
KPNA1 karyopherin alpha 1 (importin alpha 5) 0.491597
MLN motilin 0.491215
RAVER2 ribonucleoprotein, PTB-binding 2 0.490835
MMP9 matrix metallopeptidase 9 0.490454
IRF1 interferon regulatory factor 1 0.490072
CD163 CD163 molecule 0.489311
ZNF300 zinc finger protein 300 0.489311
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 0.485125
PTH parathyroid hormone 0.484744
B3GAT1 beta-1,3-glucuronyltransferase 1 0.484364
ICAM2 intercellular adhesion molecule 2 0.483985
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.483604
SEC16A SEC16 homolog A (S. cerevisiae) 0.482464
TYK2 tyrosine kinase 2 0.482084
IL27RA interleukin 27 receptor, alpha 0.481705
PNN pinin, desmosome associated protein 0.47753
PYY peptide YY 0.474498
ADAM17 ADAM metallopeptidase domain 17 0.473361
CCR7 chemokine (C-C motif) receptor 7 0.471846
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.471846
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 0.470332
IRGC immunity-related GTPase family, cinema 0.468819
CMA1 chymase 1, mast cell 0.467684
ZMIZ1 zinc finger, MIZ-type containing 1 0.463527
SELE selectin E 0.462394
GPX1 glutathione peroxidase 1 0.462016
IGFBP3 insulin-like growth factor binding protein 3 0.461261
TCERG1L transcription elongation regulator 1-like 0.460506
MORC4 MORC family CW-type zinc finger 4 0.458619
MORN2 MORN repeat containing 2 0.456355
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.455978
POMC proopiomelanocortin 0.452962
SMAD3 SMAD family member 3 0.451831
C10ORF67 chromosome 10 open reading frame 67 0.451454
INSC inscuteable homolog (Drosophila) 0.451078
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 0.449947
UBE4A ubiquitination factor E4A 0.448441
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.448441
RETN resistin 0.446558
MAPK14 mitogen-activated protein kinase 14 0.445429
EXOSC1 exosome component 1 0.4443
TRAF4 TNF receptor-associated factor 4 0.443923
KIAA1109 KIAA1109 0.442042
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.442042
MMD2 monocyte to macrophage differentiation-associated 2 0.442042
RIPK3 receptor-interacting serine-threonine kinase 3 0.442042
ERAP1 endoplasmic reticulum aminopeptidase 1 0.439034
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 0.438658
ULK1 unc-51 like autophagy activating kinase 1 0.438282
CD44 CD44 molecule (Indian blood group) 0.437906
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.43753
GPX5 glutathione peroxidase 5 0.436402
SST somatostatin 0.435651
CXCL5 chemokine (C-X-C motif) ligand 5 0.434899
GPX4 glutathione peroxidase 4 0.433397
NT5C 5', 3'-nucleotidase, cytosolic 0.433021
GNA12 guanine nucleotide binding protein (G protein) alpha 12 0.432646
IL17F interleukin 17F 0.430768
MAST3 microtubule associated serine/threonine kinase 3 0.428891
JUN jun proto-oncogene 0.427765
REEP6 receptor accessory protein 6 0.427015
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.425514
HPS6 Hermansky-Pudlak syndrome 6 0.422515
UCN urocortin 0.422515
IRAK3 interleukin-1 receptor-associated kinase 3 0.421016
PUS10 pseudouridylate synthase 10 0.420641
IL16 interleukin 16 0.419892
NCAM1 neural cell adhesion molecule 1 0.419142
CXCL16 chemokine (C-X-C motif) ligand 16 0.418768
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.416896
MMP1 matrix metallopeptidase 1 0.416147
CD34 CD34 molecule 0.413901
CLDN7 claudin 7 0.413527
NELL1 NEL-like 1 (chicken) 0.412779
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.412405
GSDMB gasdermin B 0.412405
NSL1 NSL1, MIS12 kinetochore complex component 0.410909
IL10RB interleukin 10 receptor, beta 0.410161
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.40904
LYRM4 LYR motif containing 4 0.40904
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.407545
IL15 interleukin 15 0.407545
SOD2 superoxide dismutase 2, mitochondrial 0.406051
IGFBP5 insulin-like growth factor binding protein 5 0.405305
ATG4D autophagy related 4D, cysteine peptidase 0.402318
TP53 tumor protein p53 0.402318
SPP1 secreted phosphoprotein 1 0.400453
CCDC88B coiled-coil domain containing 88B 0.398962
IL26 interleukin 26 0.396725
SBNO2 strawberry notch homolog 2 (Drosophila) 0.396725
COL1A2 collagen, type I, alpha 2 0.396353
ATG12 autophagy related 12 0.393746
SLU7 SLU7 splicing factor homolog (S. cerevisiae) 0.393746
FGF2 fibroblast growth factor 2 (basic) 0.391513
TFF1 trefoil factor 1 0.390397
CXCL2 chemokine (C-X-C motif) ligand 2 0.386679
CCL5 chemokine (C-C motif) ligand 5 0.385565
PGLYRP1 peptidoglycan recognition protein 1 0.384822
HELB helicase (DNA) B 0.384822
RNASE3 ribonuclease, RNase A family, 3 0.384079
ACP1 acid phosphatase 1, soluble 0.383708
BTN3A3 butyrophilin, subfamily 3, member A3 0.382594
CXCL12 chemokine (C-X-C motif) ligand 12 0.377402
GHRL ghrelin/obestatin prepropeptide 0.377031
USP3 ubiquitin specific peptidase 3 0.376661
AMD1 adenosylmethionine decarboxylase 1 0.37629
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 0.37555
GPC2 glypican 2 0.375179
CYLD cylindromatosis (turban tumor syndrome) 0.372587
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 0.370737
BSG basigin (Ok blood group) 0.369997
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 0.369628
MMP2 matrix metallopeptidase 2 0.368518
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.366671
PLA2G2E phospholipase A2, group IIE 0.365562
S100A8 S100 calcium binding protein A8 0.365193
CHPF2 chondroitin polymerizing factor 2 0.364454
IRF5 interferon regulatory factor 5 0.363347
FCRL3 Fc receptor-like 3 0.362609
REG1A regenerating islet-derived 1 alpha 0.362239
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 0.360026
FN1 fibronectin 1 0.359657
PROS1 protein S (alpha) 0.359289
MAPK10 mitogen-activated protein kinase 10 0.357077
TSLP thymic stromal lymphopoietin 0.356709
MUC6 mucin 6, oligomeric mucus/gel-forming 0.355604
B2M beta-2-microglobulin 0.353763
TBC1D23 TBC1 domain family, member 23 0.353395
HBA2 hemoglobin, alpha 2 0.353027
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.352659
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 0.351555
ECD ecdysoneless homolog (Drosophila) 0.350084
PTPRS protein tyrosine phosphatase, receptor type, S 0.348981
PPP3R2 protein phosphatase 3, regulatory subunit B, beta 0.348981
RORC RAR-related orphan receptor C 0.348246
NEU2 sialidase 2 (cytosolic sialidase) 0.347144
APAF1 apoptotic peptidase activating factor 1 0.342739
CCDC122 coiled-coil domain containing 122 0.341639
RAG1 recombination activating gene 1 0.340173
PDCL3 phosducin-like 3 0.339806
PODXL podocalyxin-like 0.339806
MMP12 matrix metallopeptidase 12 0.338341
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 0.337975
GAST gastrin 0.337242
NLRP6 NLR family, pyrin domain containing 6 0.333949
RRAGD Ras-related GTP binding D 0.332852
FAM84A family with sequence similarity 84, member A 0.331391
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.33066
FGF7 fibroblast growth factor 7 0.330295
ANXA5 annexin A5 0.328105
PRF1 perforin 1 (pore forming protein) 0.32774
FKBP15 FK506 binding protein 15, 133kDa 0.32774
LY96 lymphocyte antigen 96 0.327375
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.327375
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 0.326281
CCL3 chemokine (C-C motif) ligand 3 0.324823
HMGB1 high mobility group box 1 0.324458
LAMB1 laminin, beta 1 0.324094
GBGT1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 0.322273
PLG plasminogen 0.319726
USP40 ubiquitin specific peptidase 40 0.319363
SDC1 syndecan 1 0.318635
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.317182
PHB2 prohibitin 2 0.315003
THBD thrombomodulin 0.31464
IL12RB1 interleukin 12 receptor, beta 1 0.314278
DAGLB diacylglycerol lipase, beta 0.314278
NLRC4 NLR family, CARD domain containing 4 0.313552
LRG1 leucine-rich alpha-2-glycoprotein 1 0.312102
CCL11 chemokine (C-C motif) ligand 11 0.309928
ATG7 autophagy related 7 0.30848
MLNR motilin receptor 0.308118
MST1R macrophage stimulating 1 receptor 0.307757
HSPA4 heat shock 70kDa protein 4 0.305948
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.305948
KIAA0101 KIAA0101 0.305226
IRF4 interferon regulatory factor 4 0.305226
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.303781
KLK1 kallikrein 1 0.302698
TEPP testis, prostate and placenta expressed 0.302698
MUC4 mucin 4, cell surface associated 0.302337
F3 coagulation factor III (thromboplastin, tissue factor) 0.297291
CD69 CD69 molecule 0.296571
JAKMIP1 janus kinase and microtubule interacting protein 1 0.296211
HBA1 hemoglobin, alpha 1 0.295492
ACE angiotensin I converting enzyme 0.295492
PLA2G10 phospholipase A2, group X 0.295492
RETNLB resistin like beta 0.29118
TIMP3 TIMP metallopeptidase inhibitor 3 0.289386
HRAS Harvey rat sarcoma viral oncogene homolog 0.289386
CDHR2 cadherin-related family member 2 0.289027
F8 coagulation factor VIII, procoagulant component 0.286877
CLDN12 claudin 12 0.281868
CD160 CD160 molecule 0.281868
THNSL2 threonine synthase-like 2 (S. cerevisiae) 0.281868
AVIL advillin 0.276158
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.276158
NOS2 nitric oxide synthase 2, inducible 0.274732
GUSB glucuronidase, beta 0.274732
MCAM melanoma cell adhesion molecule 0.274376
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 0.274021
TRIM31 tripartite motif containing 31 0.27153
FDCSP follicular dendritic cell secreted protein 0.268332
INS insulin 0.267977
CAT catalase 0.267977
PARM1 prostate androgen-regulated mucin-like protein 1 0.266913
GGT1 gamma-glutamyltransferase 1 0.263368
IFITM1 interferon induced transmembrane protein 1 0.261952
CXCL6 chemokine (C-X-C motif) ligand 6 0.261599
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.261245
CXCL3 chemokine (C-X-C motif) ligand 3 0.255241
PRG1 p53-responsive gene 1 0.255241
CFLAR CASP8 and FADD-like apoptosis regulator 0.254536
MED28 mediator complex subunit 28 0.253831
HSF2 heat shock transcription factor 2 0.252422
TRAC T cell receptor alpha constant 0.251718
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.249608
IL4R interleukin 4 receptor 0.248905
CCR3 chemokine (C-C motif) receptor 3 0.248203
KCTD7 potassium channel tetramerization domain containing 7 0.247501
CLDN2 claudin 2 0.246799
CCL26 chemokine (C-C motif) ligand 26 0.245747
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.245396
ITGB7 integrin, beta 7 0.245046
TRNAU1AP tRNA selenocysteine 1 associated protein 1 0.245046
IFNB1 interferon, beta 1, fibroblast 0.245046
IRG1 immunoresponsive 1 homolog (mouse) 0.245046
RAG2 recombination activating gene 2 0.245046
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.243995
ATG16L2 autophagy related 16-like 2 (S. cerevisiae) 0.240847
MIR192 microRNA 192 0.240497
SEBOX SEBOX homeobox 0.240497
IL1R2 interleukin 1 receptor, type II 0.240148
PER1 period circadian clock 1 0.239799
IL33 interleukin 33 0.239799
CXCR2 chemokine (C-X-C motif) receptor 2 0.238752
CELA1 chymotrypsin-like elastase family, member 1 0.238403
IER3 immediate early response 3 0.238403
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.237706
CTSW cathepsin W 0.237009
GPR161 G protein-coupled receptor 161 0.23666
CELA3B chymotrypsin-like elastase family, member 3B 0.235268
PANX1 pannexin 1 0.23492
CLEC2D C-type lectin domain family 2, member D 0.23492
ITCH itchy E3 ubiquitin protein ligase 0.232836
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 0.232836
TNC tenascin C 0.230755
CAMP cathelicidin antimicrobial peptide 0.230063
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.230063
GIF gastric intrinsic factor (vitamin B synthesis) 0.230063
CCL8 chemokine (C-C motif) ligand 8 0.229024
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.227988
FZD5 frizzled class receptor 5 0.227642
NLRP11 NLR family, pyrin domain containing 11 0.227642
KNG1 kininogen 1 0.227297
DNTT DNA nucleotidylexotransferase 0.226952
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.223853
ATG9A autophagy related 9A 0.223509
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.221793
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.220766
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 0.220424
TRAF5 TNF receptor-associated factor 5 0.220081
IGHD3-10 immunoglobulin heavy diversity 3-10 0.219398
FAAH fatty acid amide hydrolase 0.214975
PGLYRP4 peptidoglycan recognition protein 4 0.212271
LGALS3 lectin, galactoside-binding, soluble, 3 0.211261
SLC16A6 solute carrier family 16, member 6 0.210925
COX5A cytochrome c oxidase subunit Va 0.210589
NIT2 nitrilase family, member 2 0.209583
STAT5B signal transducer and activator of transcription 5B 0.209248
CCL4 chemokine (C-C motif) ligand 4 0.209248
NME6 NME/NM23 nucleoside diphosphate kinase 6 0.208914
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 0.208914
CLDN8 claudin 8 0.208245
FLOT2 flotillin 2 0.207245
RDH10 retinol dehydrogenase 10 (all-trans) 0.206913
PF4 platelet factor 4 0.20658
PGM1 phosphoglucomutase 1 0.205916
PTBP1 polypyrimidine tract binding protein 1 0.204923
LAMB2 laminin, beta 2 (laminin S) 0.203604
GPBAR1 G protein-coupled bile acid receptor 1 0.202618
IL7R interleukin 7 receptor 0.202618
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.201308
CDX2 caudal type homeobox 2 0.201308
CXCR1 chemokine (C-X-C motif) receptor 1 0.200982
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.200982
MMP7 matrix metallopeptidase 7 0.200982
SCUBE3 signal peptide, CUB domain, EGF-like 3 0.200656
MIRLET7E microRNA let-7e 0.200656
FOLR2 folate receptor 2 (fetal) 0.199033
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.198386
PHB prohibitin 0.19742
C11ORF30 chromosome 11 open reading frame 30 0.196139
PADI4 peptidyl arginine deiminase, type IV 0.195501
MGAM maltase-glucoamylase 0.195183
CD33 CD33 molecule 0.1936
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.192344
BAX BCL2-associated X protein 0.192031
APOLD1 apolipoprotein L domain containing 1 0.192031
CD27 CD27 molecule 0.191408
MICB MHC class I polypeptide-related sequence B 0.191097
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.190476
IL27 interleukin 27 0.190168
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.188326
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.188326
VWF von Willebrand factor 0.187415
TOLLIP toll interacting protein 0.18621
ATP1A1-AS1 ATP1A1 antisense RNA 1 0.18621
PPIE peptidylprolyl isomerase E (cyclophilin E) 0.185612
SOS2 son of sevenless homolog 2 (Drosophila) 0.185313
COL7A1 collagen, type VII, alpha 1 0.185016
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 0.18472
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 0.184424
VEGFA vascular endothelial growth factor A 0.183541
RPL7P32 ribosomal protein L7 pseudogene 32 0.183541
DCLK3 doublecortin-like kinase 3 0.183248
PHF11 PHD finger protein 11 0.183248
PTBP2 polypyrimidine tract binding protein 2 0.182957
IL5 interleukin 5 0.181798
FGD1 FYVE, RhoGEF and PH domain containing 1 0.180084
TLR3 toll-like receptor 3 0.180084
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 0.179802
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.17952
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.179239
TMLHE trimethyllysine hydroxylase, epsilon 0.178682
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 0.177029
AZU1 azurocidin 1 0.177029
HMOX1 heme oxygenase 1 0.176757
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.175947
SETD2 SET domain containing 2 0.175947
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.175411
C4B complement component 4B (Chido blood group) 0.175411
KIF21B kinesin family member 21B 0.175146
IL17C interleukin 17C 0.175146
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.174881
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.174617
UBD ubiquitin D 0.173057
MRC1 mannose receptor, C type 1 0.171785
HNF4A hepatocyte nuclear factor 4, alpha 0.171785
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 0.171535
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.171286
ENO1 enolase 1, (alpha) 0.16933
HLA-G major histocompatibility complex, class I, G 0.169091
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.168854
RPS23 ribosomal protein S23 0.167915
MREG melanoregulin 0.167915
IL17RC interleukin 17 receptor C 0.167682
SPG20 spastic paraplegia 20 (Troyer syndrome) 0.166768
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.166095
CSF3 colony stimulating factor 3 (granulocyte) 0.165874
DERL3 derlin 3 0.164571
DENND1B DENN/MADD domain containing 1B 0.164571
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.163729
PGF placental growth factor 0.163523
RAB13 RAB13, member RAS oncogene family 0.163317
GC group-specific component (vitamin D binding protein) 0.162707
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.162109
PDIA4 protein disulfide isomerase family A, member 4 0.161912
MMP19 matrix metallopeptidase 19 0.161912
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.161139
CD5 CD5 molecule 0.161139
CD300LF CD300 molecule-like family member f 0.160948
VIMP VCP-interacting membrane selenoprotein 0.160948
CCL3L1 chemokine (C-C motif) ligand 3-like 1 0.160761
SEPHS1 selenophosphate synthetase 1 0.159838
MAP3K4 mitogen-activated protein kinase kinase kinase 4 0.15948
MMP13 matrix metallopeptidase 13 0.159302
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 0.158778
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.158605
KRAS Kirsten rat sarcoma viral oncogene homolog 0.158266
NLRP4 NLR family, pyrin domain containing 4 0.157602
AGER advanced glycosylation end product-specific receptor 0.157602