cortical renal glomerulopathies Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any disease of the capillary plexus in the kidney cortex (Mammalian Phenotype Ontology, MP_0000523)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000523
Similar Terms
Downloads & Tools

Genes

129 gene mutations causing the cortical renal glomerulopathies phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACTN4 actinin, alpha 4
ADM adrenomedullin
ANK1 ankyrin 1, erythrocytic
APCS amyloid P component, serum
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1QA complement component 1, q subcomponent, A chain
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
CCNI cyclin I
CCR1 chemokine (C-C motif) receptor 1
CD151 CD151 molecule (Raph blood group)
CD1D CD1d molecule
CD2AP CD2-associated protein
CD72 CD72 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFH complement factor H
CHD2 chromodomain helicase DNA binding protein 2
CLU clusterin
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A4 collagen, type IV, alpha 4
COL4A5 collagen, type IV, alpha 5
CORO1A coronin, actin binding protein, 1A
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
DKC1 dyskeratosis congenita 1, dyskerin
DNASE1 deoxyribonuclease I
DTX1 deltex 1, E3 ubiquitin ligase
E2F2 E2F transcription factor 2
ESR1 estrogen receptor 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FRAS1 Fraser extracellular matrix complex subunit 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GAS6 growth arrest-specific 6
GLIS2 GLIS family zinc finger 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GOLM1 golgi membrane protein 1
GPX7 glutathione peroxidase 7
GRM1 glutamate receptor, metabotropic 1
GSTK1 glutathione S-transferase kappa 1
HMOX1 heme oxygenase 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
HR hair growth associated
IFNG interferon, gamma
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL12RB2 interleukin 12 receptor, beta 2
INS insulin
ITGA1 integrin, alpha 1
LAMB2 laminin, beta 2 (laminin S)
LAT linker for activation of T cells
LCAT lecithin-cholesterol acyltransferase
LEP leptin
LEPR leptin receptor
LYN LYN proto-oncogene, Src family tyrosine kinase
MAN2A1 mannosidase, alpha, class 2A, member 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MET MET proto-oncogene, receptor tyrosine kinase
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MPV17 MpV17 mitochondrial inner membrane protein
MTA2 metastasis associated 1 family, member 2
MTSS1 metastasis suppressor 1
MTUS1 microtubule associated tumor suppressor 1
MYH9 myosin, heavy chain 9, non-muscle
MYO1E myosin IE
NFE2L2 nuclear factor, erythroid 2-like 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
PDCD1 programmed cell death 1
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PGM3 phosphoglucomutase 3
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PKN1 protein kinase N1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POLB polymerase (DNA directed), beta
PRDX6 peroxiredoxin 6
PRKCD protein kinase C, delta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RC3H1 ring finger and CCCH-type domains 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REN renin
RET ret proto-oncogene
RPL22 ribosomal protein L22
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SCARF1 scavenger receptor class F, member 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCTR secretin receptor
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIAE sialic acid acetylesterase
SIRT1 sirtuin 1
SOCS1 suppressor of cytokine signaling 1
SPTA1 spectrin, alpha, erythrocytic 1
SPTB spectrin, beta, erythrocytic
SYK spleen tyrosine kinase
TAL1 T-cell acute lymphocytic leukemia 1
TANK TRAF family member-associated NFKB activator
TK1 thymidine kinase 1, soluble
TLR8 toll-like receptor 8
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNIP1 TNFAIP3 interacting protein 1
TNS1 tensin 1
TNS2 tensin 2
TOP3B topoisomerase (DNA) III beta
TRAF3IP2 TRAF3 interacting protein 2
TREX1 three prime repair exonuclease 1
TROVE2 TROVE domain family, member 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUSC2 tumor suppressor candidate 2
UNC93B1 unc-93 homolog B1 (C. elegans)
VEGFA vascular endothelial growth factor A
WAS Wiskott-Aldrich syndrome
WT1 Wilms tumor 1