cortical lewy body Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Cytoplasmic inclusion similar to a classical Lewy body but lacking a halo of protein fibrils. (Gene Ontology, GO_0097415)
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Genes

36 proteins co-occuring with the cortical lewy body cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
LRRK2 leucine-rich repeat kinase 2 1.10205
APOE apolipoprotein E 1.01635
BCHE butyrylcholinesterase 0.847451
UBC ubiquitin C 0.785986
RPS27A ribosomal protein S27a 0.758615
UBB ubiquitin B 0.740965
TP73 tumor protein p73 0.695148
HTRA2 HtrA serine peptidase 2 0.692516
MAPT microtubule-associated protein tau 0.605706
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.584268
SNCAIP synuclein, alpha interacting protein 0.579251
PSEN1 presenilin 1 0.404804
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.404415
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.390455
CLU clusterin 0.362422
APP amyloid beta (A4) precursor protein 0.361277
RAB11A RAB11A, member RAS oncogene family 0.356324
COMT catechol-O-methyltransferase 0.341151
PSEN2 presenilin 2 0.334356
FMR1 fragile X mental retardation 1 0.324951
MCF2 MCF.2 cell line derived transforming sequence 0.3227
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 0.31596
PVALB parvalbumin 0.314091
GSTP1 glutathione S-transferase pi 1 0.298084
SYP synaptophysin 0.286245
DRD2 dopamine receptor D2 0.266408
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.260931
AIF1 allograft inflammatory factor 1 0.235249
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.21681
MAOB monoamine oxidase B 0.214017
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.213669
MAP1B microtubule-associated protein 1B 0.199325
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.191777
CRYAB crystallin, alpha B 0.180339
TH tyrosine hydroxylase 0.157397
APAF1 apoptotic peptidase activating factor 1 0.157218