corneal disease Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:10124
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Genes

92 genes associated with the disease corneal disease in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
LRRK1 leucine-rich repeat kinase 1 1.96585
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.71314
LPAR1 lysophosphatidic acid receptor 1 1.65612
FNDC3B fibronectin type III domain containing 3B 1.65612
COL5A1 collagen, type V, alpha 1 1.65612
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 1.59102
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.54786
TMEM248 transmembrane protein 248 1.54533
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 1.54347
SMAD3 SMAD family member 3 1.53058
ARID5B AT rich interactive domain 5B (MRF1-like) 1.52524
TMEM132C transmembrane protein 132C 1.51269
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 1.50906
CHSY1 chondroitin sulfate synthase 1 1.48714
LINC00578 long intergenic non-protein coding RNA 578 1.42467
USP37 ubiquitin specific peptidase 37 1.42421
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.35834
SOX5 SRY (sex determining region Y)-box 5 1.3384
PTPRD protein tyrosine phosphatase, receptor type, D 1.3308
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 1.33
VAX2 ventral anterior homeobox 2 1.28906
LOC729173 uncharacterized LOC729173 1.25477
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 1.23226
MACROD2 MACRO domain containing 2 1.21577
TCF4 transcription factor 4 1.19386
DNAH5 dynein, axonemal, heavy chain 5 1.19386
UBXN4 UBX domain protein 4 1.19386
AKAP13 A kinase (PRKA) anchor protein 13 1.17002
TTLL4 tubulin tyrosine ligase-like family member 4 1.16305
MAML2 mastermind-like 2 (Drosophila) 1.14463
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 1.14463
BICC1 BicC family RNA binding protein 1 1.10764
CS citrate synthase 1.09959
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.07992
KCTD7 potassium channel tetramerization domain containing 7 1.079
LMO7 LIM domain 7 1.07599
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.07599
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 1.07599
ADORA3 adenosine A3 receptor 1.06509
LOC400655 uncharacterized LOC400655 1.04872
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 1.04846
WIPF3 WAS/WASL interacting protein family, member 3 1.04846
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 1.04846
CLEC12B C-type lectin domain family 12, member B 1.02476
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 1.02476
NUB1 negative regulator of ubiquitin-like proteins 1 1.01287
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.00407
STK32B serine/threonine kinase 32B 1.00407
THSD7B thrombospondin, type I, domain containing 7B 0.986376
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.971169
USP53 ubiquitin specific peptidase 53 0.971169
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.950418
SETBP1 SET binding protein 1 0.93638
NCAM2 neural cell adhesion molecule 2 0.886521
LRP1B low density lipoprotein receptor-related protein 1B 0.814931
METTL4 methyltransferase like 4 0.772076
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.724858
PARVG parvin, gamma 0.720957
BSX brain-specific homeobox 0.720744
C20ORF27 chromosome 20 open reading frame 27 0.690978
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.687994
LOC100505718 0.679961
ELP3 elongator acetyltransferase complex subunit 3 0.677559
ADAM23 ADAM metallopeptidase domain 23 0.674805
WDR64 WD repeat domain 64 0.663004
CHURC1 churchill domain containing 1 0.662072
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.659337
LRRC4C leucine rich repeat containing 4C 0.627673
TRIM58 tripartite motif containing 58 0.615445
GLIS1 GLIS family zinc finger 1 0.610366
HYDIN HYDIN, axonemal central pair apparatus protein 0.600187
PCNT pericentrin 0.588054
RANBP9 RAN binding protein 9 0.586586
LRRTM1 leucine rich repeat transmembrane neuronal 1 0.552202
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.545546
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.526921
WDFY2 WD repeat and FYVE domain containing 2 0.525463
LOC100506532 uncharacterized LOC100506532 0.500649
TIMP3 TIMP metallopeptidase inhibitor 3 0.49941
KDM4C lysine (K)-specific demethylase 4C 0.498914
COL8A2 collagen, type VIII, alpha 2 0.486213
ADPRHL2 ADP-ribosylhydrolase like 2 0.480254
AKAP6 A kinase (PRKA) anchor protein 6 0.454317
IDO2 indoleamine 2,3-dioxygenase 2 0.450176
FAM53B family with sequence similarity 53, member B 0.447649
TRAPPC3 trafficking protein particle complex 3 0.443353
FAM175B family with sequence similarity 175, member B 0.441647
PTPRG protein tyrosine phosphatase, receptor type, G 0.438494
LINC00290 long intergenic non-protein coding RNA 290 0.435351
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 0.417269
SDK1 sidekick cell adhesion molecule 1 0.416392
PIAS2 protein inhibitor of activated STAT, 2 0.412143