convolamine-5876 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the convolamine-5876 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAM28 ADAM metallopeptidase domain 28
AGRP agouti related neuropeptide
AK5 adenylate kinase 5
AKT3 v-akt murine thymoma viral oncogene homolog 3
APOE apolipoprotein E
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
BAIAP3 BAI1-associated protein 3
BCAM basal cell adhesion molecule (Lutheran blood group)
C15ORF39 chromosome 15 open reading frame 39
C19ORF73 chromosome 19 open reading frame 73
C1QTNF1 C1q and tumor necrosis factor related protein 1
CA11 carbonic anhydrase XI
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACTIN cactin, spliceosome C complex subunit
CCDC57 coiled-coil domain containing 57
CCNJL cyclin J-like
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
COL1A2 collagen, type I, alpha 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DOC2A double C2-like domains, alpha
DPY19L1 dpy-19-like 1 (C. elegans)
DVL2 dishevelled segment polarity protein 2
DZIP1 DAZ interacting zinc finger protein 1
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EXO5 exonuclease 5
FOXN2 forkhead box N2
GJA9 gap junction protein, alpha 9, 59kDa
GNS glucosamine (N-acetyl)-6-sulfatase
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GSTTP1 glutathione S-transferase theta pseudogene 1
HNF1A HNF1 homeobox A
HOXC4 homeobox C4
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLRF1 killer cell lectin-like receptor subfamily F, member 1
LAMA4 laminin, alpha 4
LIMK2 LIM domain kinase 2
LMNA lamin A/C
LRRK1 leucine-rich repeat kinase 1
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAP7D3 MAP7 domain containing 3
MAPT microtubule-associated protein tau
MKL1 megakaryoblastic leukemia (translocation) 1
MYF5 myogenic factor 5
N4BP1 NEDD4 binding protein 1
NCKIPSD NCK interacting protein with SH3 domain
NOX1 NADPH oxidase 1
NPY4R neuropeptide Y receptor Y4
PDZD7 PDZ domain containing 7
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
RAD52 RAD52 homolog (S. cerevisiae)
RAD54B RAD54 homolog B (S. cerevisiae)
RANBP1 RAN binding protein 1
REEP1 receptor accessory protein 1
RGS17 regulator of G-protein signaling 17
SARM1 sterile alpha and TIR motif containing 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SELL selectin L
SETD8 SET domain containing (lysine methyltransferase) 8
SETDB1 SET domain, bifurcated 1
SETX senataxin
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIKE1 suppressor of IKBKE 1
SIRT6 sirtuin 6
SLC45A2 solute carrier family 45, member 2
SLC46A3 solute carrier family 46, member 3
SMAD1 SMAD family member 1
SPTBN1 spectrin, beta, non-erythrocytic 1
STAC SH3 and cysteine rich domain
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STARD3 StAR-related lipid transfer (START) domain containing 3
SYCP2 synaptonemal complex protein 2
TACSTD2 tumor-associated calcium signal transducer 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBC1D17 TBC1 domain family, member 17
TBC1D22A TBC1 domain family, member 22A
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TRAPPC9 trafficking protein particle complex 9
TXNRD3 thioredoxin reductase 3
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UTRN utrophin
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WEE1 WEE1 G2 checkpoint kinase
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
AARS alanyl-tRNA synthetase
ALS2CL ALS2 C-terminal like
AMT aminomethyltransferase
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C11ORF30 chromosome 11 open reading frame 30
CAPN5 calpain 5
CCNT1 cyclin T1
CDC45 cell division cycle 45
CLDN14 claudin 14
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRYBA2 crystallin, beta A2
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DEPTOR DEP domain containing MTOR-interacting protein
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EDC3 enhancer of mRNA decapping 3
EMC6 ER membrane protein complex subunit 6
FAM53B family with sequence similarity 53, member B
FHOD1 formin homology 2 domain containing 1
FOXC1 forkhead box C1
FPGS folylpolyglutamate synthase
GLDC glycine dehydrogenase (decarboxylating)
GLT8D2 glycosyltransferase 8 domain containing 2
GRAMD4 GRAM domain containing 4
HIST1H2AI histone cluster 1, H2ai
HOOK1 hook microtubule-tethering protein 1
HOXA1 homeobox A1
HOXA4 homeobox A4
HS1BP3 HCLS1 binding protein 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNA14 interferon, alpha 14
IGFLR1 IGF-like family receptor 1
INF2 inverted formin, FH2 and WH2 domain containing
INTS9 integrator complex subunit 9
IPP intracisternal A particle-promoted polypeptide
IRF1 interferon regulatory factor 1
KIAA0894 KIAA0894 protein
KIF13B kinesin family member 13B
LAMA5 laminin, alpha 5
LOC100286895 cell division cycle 27 homolog pseudogene
LRRC6 leucine rich repeat containing 6
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP6D1 MAP6 domain containing 1
MCTP1 multiple C2 domains, transmembrane 1
MED15 mediator complex subunit 15
MEIS1 Meis homeobox 1
METRN meteorin, glial cell differentiation regulator
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MVP major vault protein
NDE1 nudE neurodevelopment protein 1
NPFFR1 neuropeptide FF receptor 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR3C2 nuclear receptor subfamily 3, group C, member 2
OPLAH 5-oxoprolinase (ATP-hydrolysing)
PEX26 peroxisomal biogenesis factor 26
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHKG2 phosphorylase kinase, gamma 2 (testis)
PRR14L proline rich 14-like
PRSS2 protease, serine, 2 (trypsin 2)
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PTGES2 prostaglandin E synthase 2
PTGFR prostaglandin F receptor (FP)
RBBP5 retinoblastoma binding protein 5
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF122 ring finger protein 122
RPL13P5 ribosomal protein L13 pseudogene 5
SCN1B sodium channel, voltage gated, type I beta subunit
SCRN3 secernin 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SMAD7 SMAD family member 7
SOD3 superoxide dismutase 3, extracellular
SPAG7 sperm associated antigen 7
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
SYNPO synaptopodin
TAGLN3 transgelin 3
TESK2 testis-specific kinase 2
TM6SF1 transmembrane 6 superfamily member 1
TMC7 transmembrane channel-like 7
TMEM156 transmembrane protein 156
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPK1 thiamin pyrophosphokinase 1
TPST2 tyrosylprotein sulfotransferase 2
TRDMT1 tRNA aspartic acid methyltransferase 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TTLL7 tubulin tyrosine ligase-like family member 7
USP20 ubiquitin specific peptidase 20
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
ZBTB48 zinc finger and BTB domain containing 48
ZFHX3 zinc finger homeobox 3
ZNF230 zinc finger protein 230
ZNF426 zinc finger protein 426
ZNF442 zinc finger protein 442
ZNF665 zinc finger protein 665
ZNF668 zinc finger protein 668
ZNHIT2 zinc finger, HIT-type containing 2