contractile ring Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A cytoskeletal structure composed of filamentous protein that forms beneath the membrane of many cells or organelles, in the plane of cell or organelle division. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells or organelles. (Gene Ontology, GO_0070938)
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Genes

158 proteins co-occuring with the contractile ring cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CASR calcium-sensing receptor 3.64801
ANLN anillin, actin binding protein 2.2971
PTH parathyroid hormone 2.18153
CARS cysteinyl-tRNA synthetase 2.14132
NPSR1 neuropeptide S receptor 1 1.93972
ECT2 epithelial cell transforming 2 1.67022
FMN1 formin 1 1.51976
PTHLH parathyroid hormone-like hormone 1.36802
RACGAP1 Rac GTPase activating protein 1 1.31142
GPRC6A G protein-coupled receptor, class C, group 6, member A 1.26551
SEPT5 septin 5 1.23348
GPR182 G protein-coupled receptor 182 1.10409
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.08526
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 1.00645
KIF23 kinesin family member 23 0.956874
GRM1 glutamate receptor, metabotropic 1 0.85342
PLK1 polo-like kinase 1 0.785986
MYLK myosin light chain kinase 0.683771
LPAR5 lysophosphatidic acid receptor 5 0.669858
STK38 serine/threonine kinase 38 0.654741
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 0.646574
CDC42 cell division cycle 42 0.646145
KRT4 keratin 4, type II 0.628613
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.612895
FGF23 fibroblast growth factor 23 0.608663
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) 0.593912
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.591812
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.591392
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.590973
FLNA filamin A, alpha 0.590133
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 0.588875
CDC14A cell division cycle 14A 0.580504
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.575912
MAST4 microtubule associated serine/threonine kinase family member 4 0.563847
CALB2 calbindin 2 0.559285
CDK1 cyclin-dependent kinase 1 0.558871
TJP1 tight junction protein 1 0.556387
C6ORF15 chromosome 6 open reading frame 15 0.552251
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.551425
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.550599
GPR84 G protein-coupled receptor 84 0.54936
KIF14 kinesin family member 14 0.53413
CXADR coxsackie virus and adenovirus receptor 0.532488
STC1 stanniocalcin 1 0.524294
SEPT2 septin 2 0.514085
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.512047
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 0.4865
FFAR4 free fatty acid receptor 4 0.484483
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) 0.483273
RGS4 regulator of G-protein signaling 4 0.47442
EXOC1 exocyst complex component 1 0.470406
MYLK3 myosin light chain kinase 3 0.4608
DIAPH3 diaphanous-related formin 3 0.458803
TBL1X transducin (beta)-like 1X-linked 0.458006
AURKB aurora kinase B 0.449643
AQP2 aquaporin 2 (collecting duct) 0.429859
PKP4 plakophilin 4 0.428284
PFN1 profilin 1 0.428284
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.421604
CALCA calcitonin-related polypeptide alpha 0.416902
MORN1 MORN repeat containing 1 0.414555
RHOD ras homolog family member D 0.410259
IQGAP3 IQ motif containing GTPase activating protein 3 0.404804
MAPK14 mitogen-activated protein kinase 14 0.403248
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) 0.402081
MYO5A myosin VA (heavy chain 12, myoxin) 0.399751
TPM1 tropomyosin 1 (alpha) 0.398199
KIF12 kinesin family member 12 0.395485
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.391228
PFN4 profilin family, member 4 0.384665
TBL1Y transducin (beta)-like 1, Y-linked 0.378122
EVL Enah/Vasp-like 0.373899
PFN2 profilin 2 0.37045
MYH10 myosin, heavy chain 10, non-muscle 0.37045
CALB1 calbindin 1, 28kDa 0.370067
ALX1 ALX homeobox 1 0.367006
KL klotho 0.359371
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.358609
CA3 carbonic anhydrase III 0.357467
MEN1 multiple endocrine neoplasia I 0.346829
RAP2B RAP2B, member of RAS oncogene family 0.324201
SEPT7 septin 7 0.319702
SAR1A secretion associated, Ras related GTPase 1A 0.317456
ARF3 ADP-ribosylation factor 3 0.317082
RAB1B RAB1B, member RAS oncogene family 0.314091
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.308867
DUSP12 dual specificity phosphatase 12 0.308122
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.305888
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.294748
GAST gastrin 0.291047
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.290308
KAZN kazrin, periplakin interacting protein 0.283663
WIPF1 WAS/WASL interacting protein family, member 1 0.279612
TJP3 tight junction protein 3 0.279612
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.277038
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.270068
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.269701
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.269335
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.267871
PLCG1 phospholipase C, gamma 1 0.266408
TRIP10 thyroid hormone receptor interactor 10 0.262755
INCENP inner centromere protein antigens 135/155kDa 0.25438
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.251839
DUSP8 dual specificity phosphatase 8 0.250751
CSPP1 centrosome and spindle pole associated protein 1 0.250389
CA2 carbonic anhydrase II 0.250026
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.243158
PVALB parvalbumin 0.240276
TJP2 tight junction protein 2 0.239197
FFAR2 free fatty acid receptor 2 0.236683
GPR119 G protein-coupled receptor 119 0.235249
TNF tumor necrosis factor 0.233101
IQGAP1 IQ motif containing GTPase activating protein 1 0.232744
BCAP31 B-cell receptor-associated protein 31 0.225267
CGN cingulin 0.220321
FLNB filamin B, beta 0.219265
DNAH8 dynein, axonemal, heavy chain 8 0.21646
EXOSC8 exosome component 8 0.215761
MYH9 myosin, heavy chain 9, non-muscle 0.214714
STAMBP STAM binding protein 0.214714
GCM2 glial cells missing homolog 2 (Drosophila) 0.212974
GARS glycyl-tRNA synthetase 0.21228
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.209169
ARHGAP18 Rho GTPase activating protein 18 0.203361
BGLAP bone gamma-carboxyglutamate (gla) protein 0.203022
STARD13 StAR-related lipid transfer (START) domain containing 13 0.201672
LRG1 leucine-rich alpha-2-glycoprotein 1 0.200999
IVL involucrin 0.200328
PRKCD protein kinase C, delta 0.197993
F2 coagulation factor II (thrombin) 0.196999
MYLK2 myosin light chain kinase 2 0.18859
CAV1 caveolin 1, caveolae protein, 22kDa 0.187646
LIMA1 LIM domain and actin binding 1 0.186397
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.186397
EXOC7 exocyst complex component 7 0.186087
KMT2E lysine (K)-specific methyltransferase 2E 0.183328
MGAM maltase-glucoamylase 0.179459
KLHL2 kelch-like family member 2 0.177724
PANK1 pantothenate kinase 1 0.175466
TMOD4 tropomodulin 4 (muscle) 0.175188
CHKA choline kinase alpha 0.165697
ALPPL2 alkaline phosphatase, placental-like 2 0.16477
ALPL alkaline phosphatase, liver/bone/kidney 0.164542
ALPP alkaline phosphatase, placental 0.164315
SPP1 secreted phosphoprotein 1 0.161905
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 0.161068
RDX radixin 0.158315
CKAP5 cytoskeleton associated protein 5 0.158129
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.156342
FMNL1 formin-like 1 0.156342
HBG1 hemoglobin, gamma A 0.13032
WAS Wiskott-Aldrich syndrome 0.130004
METAP1 methionyl aminopeptidase 1 0.129484
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.129265
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.129245
OCLN occludin 0.129204
TRPM5 transient receptor potential cation channel, subfamily M, member 5 0.12898
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.128538