condensed nuclear chromosome Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure that remains in the nucleus. (Gene Ontology, GO_0000794)
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Genes

280 proteins co-occuring with the condensed nuclear chromosome cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SYCP3 synaptonemal complex protein 3 2.43676
MLH1 mutL homolog 1 2.15663
SPO11 SPO11 meiotic protein covalently bound to DSB 2.15298
SYCP1 synaptonemal complex protein 1 2.0206
MSH4 mutS homolog 4 1.78517
RAD51 RAD51 recombinase 1.776
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 1.64733
SYCP2 synaptonemal complex protein 2 1.63361
SMC1B structural maintenance of chromosomes 1B 1.59141
STAG3 stromal antigen 3 1.59083
SMC3 structural maintenance of chromosomes 3 1.49606
RAD9A RAD9 homolog A (S. pombe) 1.44008
DMC1 DNA meiotic recombinase 1 1.41306
HORMAD1 HORMA domain containing 1 1.35102
MSH5 mutS homolog 5 1.34774
RAD17 RAD17 homolog (S. pombe) 1.34011
SYCE2 synaptonemal complex central element protein 2 1.32979
SYCE1 synaptonemal complex central element protein 1 1.326
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) 1.30819
HUS1 HUS1 checkpoint homolog (S. pombe) 1.30121
REC8 REC8 meiotic recombination protein 1.25127
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 1.22568
TEX12 testis expressed 12 1.18954
RAD21 RAD21 homolog (S. pombe) 1.17055
TOPBP1 topoisomerase (DNA) II binding protein 1 1.16542
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 1.1562
ATR ATR serine/threonine kinase 1.14341
HORMAD2 HORMA domain containing 2 1.11123
STRA8 stimulated by retinoic acid 8 1.08882
MLH3 mutL homolog 3 1.05589
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 1.03378
ATM ATM serine/threonine kinase 1.02032
MSH2 mutS homolog 2 1.01933
NF1 neurofibromin 1 1.00448
TRIP13 thyroid hormone receptor interactor 13 0.968401
HSPA2 heat shock 70kDa protein 2 0.926543
MEI1 meiosis inhibitor 1 0.904138
RNF212 ring finger protein 212 0.891169
UBR2 ubiquitin protein ligase E3 component n-recognin 2 0.888397
RAD50 RAD50 homolog (S. cerevisiae) 0.869505
SMC1A structural maintenance of chromosomes 1A 0.82037
H2AFX H2A histone family, member X 0.81257
BRCA1 breast cancer 1, early onset 0.811193
WDR61 WD repeat domain 61 0.803855
SPATA22 spermatogenesis associated 22 0.800645
TEX11 testis expressed 11 0.792396
FETUB fetuin B 0.775471
SALL4 spalt-like transcription factor 4 0.744574
DOCK11 dedicator of cytokinesis 11 0.740515
RFC2 replication factor C (activator 1) 2, 40kDa 0.735565
RFC3 replication factor C (activator 1) 3, 38kDa 0.732422
RFC4 replication factor C (activator 1) 4, 37kDa 0.728389
ATRIP ATR interacting protein 0.727941
AURKB aurora kinase B 0.721242
ZNF83 zinc finger protein 83 0.716791
PCNA proliferating cell nuclear antigen 0.691202
TEX15 testis expressed 15 0.679413
TEX19 testis expressed 19 0.679413
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.675499
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.662935
UBE2B ubiquitin-conjugating enzyme E2B 0.662935
DMRTB1 DMRT-like family B with proline-rich C-terminal, 1 0.662072
BRCA2 breast cancer 2, early onset 0.657326
SLC39A4 solute carrier family 39 (zinc transporter), member 4 0.637578
RAD54B RAD54 homolog B (S. cerevisiae) 0.637578
ZNF99 zinc finger protein 99 0.632024
FAM9B family with sequence similarity 9, member B 0.628613
FAM9A family with sequence similarity 9, member A 0.628613
RAX retina and anterior neural fold homeobox 0.626483
DAZL deleted in azoospermia-like 0.622229
SFR1 SWI5-dependent recombination repair 1 0.617557
SWI5 SWI5 recombination repair homolog (yeast) 0.617557
MCM8 minichromosome maintenance complex component 8 0.601909
HIST1H1T histone cluster 1, H1t 0.600644
SMC6 structural maintenance of chromosomes 6 0.594332
FBN2 fibrillin 2 0.581758
ZFP62 ZFP62 zinc finger protein 0.579669
MAU2 MAU2 sister chromatid cohesion factor 0.572578
ZNF354A zinc finger protein 354A 0.570913
RFC1 replication factor C (activator 1) 1, 145kDa 0.567169
FAM9C family with sequence similarity 9, member C 0.565508
SUCO SUN domain containing ossification factor 0.563432
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.546472
SLC39A2 solute carrier family 39 (zinc transporter), member 2 0.530847
INCENP inner centromere protein antigens 135/155kDa 0.527979
PRDM9 PR domain containing 9 0.520206
SBK1 SH3 domain binding kinase 1 0.516124
TRIM61 tripartite motif containing 61 0.510826
SYCP2L synaptonemal complex protein 2-like 0.503099
MTBP MDM2 binding protein 0.500664
DBT dihydrolipoamide branched chain transacylase E2 0.500258
SMC2 structural maintenance of chromosomes 2 0.495395
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2 0.494585
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.490135
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.481661
H3F3A H3 histone, family 3A 0.478038
H3F3B H3 histone, family 3B (H3.3B) 0.478038
BCAS2 breast carcinoma amplified sequence 2 0.477636
RAD18 RAD18 E3 ubiquitin protein ligase 0.475625
SKA3 spindle and kinetochore associated complex subunit 3 0.475625
SMC5 structural maintenance of chromosomes 5 0.468802
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E 0.468802
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.4676
NKX1-1 NK1 homeobox 1 0.461599
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) 0.461199
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.458803
SUMO1 small ubiquitin-like modifier 1 0.45641
PLK2 polo-like kinase 2 0.456012
MNT MAX network transcriptional repressor 0.455613
SOHLH1 spermatogenesis and oogenesis specific basic helix-loop-helix 1 0.454019
MEIG1 meiosis/spermiogenesis associated 1 0.453621
PLK1 polo-like kinase 1 0.445275
BLM Bloom syndrome, RecQ helicase-like 0.444085
HMX3 H6 family homeobox 3 0.43696
SKA1 spindle and kinetochore associated complex subunit 1 0.43696
MIR223 microRNA 223 0.436565
AGA aspartylglucosaminidase 0.434196
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 0.431829
MFSD2A major facilitator superfamily domain containing 2A 0.430253
NASP nuclear autoantigenic sperm protein (histone-binding) 0.425924
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.424353
COPS2 COP9 signalosome subunit 2 0.419252
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.418468
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.418077
SUN3 Sad1 and UNC84 domain containing 3 0.41612
RAD52 RAD52 homolog (S. cerevisiae) 0.41221
CDC7 cell division cycle 7 0.411039
MPG N-methylpurine-DNA glycosylase 0.409479
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.407529
GEN1 GEN1 Holliday junction 5' flap endonuclease 0.40714
TSGA10 testis specific, 10 0.404415
BNC2 basonuclin 2 0.397035
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.392388
WAPAL wings apart-like homolog (Drosophila) 0.389682
S100A12 S100 calcium binding protein A12 0.37966
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 0.37966
TECTA tectorin alpha 0.378122
POMC proopiomelanocortin 0.372366
CDK10 cyclin-dependent kinase 10 0.362422
NOVA1 neuro-oncological ventral antigen 1 0.360133
MCC mutated in colorectal cancers 0.360133
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) 0.357847
NIPBL Nipped-B homolog (Drosophila) 0.357847
CHEK1 checkpoint kinase 1 0.355563
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.351002
AURKC aurora kinase C 0.351002
PSMC3IP PSMC3 interacting protein 0.345692
PDS5B PDS5 cohesin associated factor B 0.341151
CCNA1 cyclin A1 0.338128
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 0.332472
HIST1H2AD histone cluster 1, H2ad 0.330966
HIST1H2AJ histone cluster 1, H2aj 0.330966
H2AFJ H2A histone family, member J 0.330966
HIST1H2AM histone cluster 1, H2am 0.330589
HIST1H2AH histone cluster 1, H2ah 0.330589
HIST1H2AG histone cluster 1, H2ag 0.329461
RPA3 replication protein A3, 14kDa 0.329084
MUS81 MUS81 structure-specific endonuclease subunit 0.329084
H2AFY2 H2A histone family, member Y2 0.327581
MSH3 mutS homolog 3 0.327205
HIST1H2AB histone cluster 1, H2ab 0.327205
HIST1H2AE histone cluster 1, H2ae 0.327205
H2AFV H2A histone family, member V 0.326829
BIN3 bridging integrator 3 0.326829
SUN1 Sad1 and UNC84 domain containing 1 0.325702
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 0.325327
CPNE1 copine I 0.324951
H2AFB1 H2A histone family, member B1 0.323825
VAX1 ventral anterior homeobox 1 0.32195
H2AFB2 H2A histone family, member B2 0.320826
JAKMIP1 janus kinase and microtubule interacting protein 1 0.319328
H2AFY H2A histone family, member Y 0.317456
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.31596
PDCD2 programmed cell death 2 0.314465
EPT1 ethanolaminephosphotransferase 1 0.314465
XPC xeroderma pigmentosum, complementation group C 0.308867
CCNC cyclin C 0.304027
ZBTB14 zinc finger and BTB domain containing 14 0.302168
PDCL2 phosducin-like 2 0.301054
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.293637
SPACA1 sperm acrosome associated 1 0.289569
MUTYH mutY homolog 0.286245
ZNF501 zinc finger protein 501 0.283295
ZNF629 zinc finger protein 629 0.283295
ZNF763 zinc finger protein 763 0.283295
ZNF569 zinc finger protein 569 0.283295
KLK15 kallikrein-related peptidase 15 0.282189
CDK11A cyclin-dependent kinase 11A 0.281453
ZNF44 zinc finger protein 44 0.281453
HSPA1L heat shock 70kDa protein 1-like 0.278877
BEGAIN brain-enriched guanylate kinase-associated 0.278877
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.278509
RAD54L RAD54-like (S. cerevisiae) 0.277774
MIR203A microRNA 203a 0.277406
BCL6B B-cell CLL/lymphoma 6, member B 0.276304
TRIT1 tRNA isopentenyltransferase 1 0.274835
APITD1 apoptosis-inducing, TAF9-like domain 1 0.274835
SST somatostatin 0.273367
NUF2 NUF2, NDC80 kinetochore complex component 0.270434
USP9Y ubiquitin specific peptidase 9, Y-linked 0.270068
PRL prolactin 0.269335
SIX6 SIX homeobox 6 0.268603
SKA2 spindle and kinetochore associated complex subunit 2 0.268603
DIDO1 death inducer-obliterator 1 0.268603
RAI1 retinoic acid induced 1 0.267871
MAP3K4 mitogen-activated protein kinase kinase kinase 4 0.267139
F2 coagulation factor II (thrombin) 0.266774
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 0.26312
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.262025
ZNF436 zinc finger protein 436 0.26166
MNS1 meiosis-specific nuclear structural 1 0.260202
NYX nyctalopin 0.255834
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.255834
GYLTL1B glycosyltransferase-like 1B 0.254017
KRTAP1-3 keratin associated protein 1-3 0.254017
WDR92 WD repeat domain 92 0.252202
CKS2 CDC28 protein kinase regulatory subunit 2 0.251476
HELLS helicase, lymphoid-specific 0.246046
OPLAH 5-oxoprolinase (ATP-hydrolysing) 0.238478
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 0.234174
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.233817
UNC5A unc-5 homolog A (C. elegans) 0.228464
NEGR1 neuronal growth regulator 1 0.225622
GHRH growth hormone releasing hormone 0.225267
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 0.224558
RCN1 reticulocalbin 1, EF-hand calcium binding domain 0.224558
REV1 REV1, polymerase (DNA directed) 0.223143
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.221378
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 0.218212
POU5F1B POU class 5 homeobox 1B 0.21681
KRTAP1-1 keratin associated protein 1-1 0.214714
GLYAT glycine-N-acyltransferase 0.214366
GDF9 growth differentiation factor 9 0.208137
CASC5 cancer susceptibility candidate 5 0.207794
HSPA1B heat shock 70kDa protein 1B 0.207451
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.203361
SETX senataxin 0.201672
PTGDR prostaglandin D2 receptor (DP) 0.19733
CRYBA1 crystallin, beta A1 0.195353
SPIN1 spindlin 1 0.190814
MFRP membrane frizzled-related protein 0.190814
MAGEA4 melanoma antigen family A4 0.189857
SRY sex determining region Y 0.189222
STS steroid sulfatase (microsomal), isozyme S 0.18859
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.186397
SGOL1 shugoshin-like 1 (S. pombe) 0.18516
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.184853
H1FOO H1 histone family, member O, oocyte-specific 0.183328
PPP6C protein phosphatase 6, catalytic subunit 0.183025
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 0.183025
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.182422
ZNF135 zinc finger protein 135 0.181823
PAX6 paired box 6 0.18093
FANCD2 Fanconi anemia, complementation group D2 0.180339
PPP5C protein phosphatase 5, catalytic subunit 0.178588
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.177724
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.174911
NEK2 NIMA-related kinase 2 0.174635
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.173543
GML glycosylphosphatidylinositol anchored molecule like 0.173003
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.173003
NPM2 nucleophosmin/nucleoplasmin 2 0.171673
CLGN calmegin 0.171673
GPI glucose-6-phosphate isomerase 0.170888
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.168598
SPEG SPEG complex locus 0.167125
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.166884
CASQ2 calsequestrin 2 (cardiac muscle) 0.166405
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.165463
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.164315
UGCG UDP-glucose ceramide glucosyltransferase 0.163865
RECQL5 RecQ protein-like 5 0.162117
RPL30 ribosomal protein L30 0.161905
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.159074
POU5F1 POU class 5 homeobox 1 0.158882
BAG6 BCL2-associated athanogene 6 0.158502
SON SON DNA binding protein 0.158315
PTDSS1 phosphatidylserine synthase 1 0.158315
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.15776
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 0.157397