complete embryonic lethality between somite formation and embryo turning Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9) (Mammalian Phenotype Ontology, MP_0011097)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011097
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Genes

72 gene mutations causing the complete embryonic lethality between somite formation and embryo turning phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACLY ATP citrate lyase
ADNP activity-dependent neuroprotector homeobox
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
BMP5 bone morphogenetic protein 5
BRCA2 breast cancer 2, early onset
C10ORF2 chromosome 10 open reading frame 2
CENPJ centromere protein J
CENPU centromere protein U
CHRD chordin
COPS3 COP9 signalosome subunit 3
CRIPT cysteine-rich PDZ-binding protein
CYFIP1 cytoplasmic FMR1 interacting protein 1
DIDO1 death inducer-obliterator 1
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC3 excision repair cross-complementation group 3
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FBXL5 F-box and leucine-rich repeat protein 5
FGFR1 fibroblast growth factor receptor 1
GATA4 GATA binding protein 4
GLUL glutamate-ammonia ligase
GPX4 glutathione peroxidase 4
HK2 hexokinase 2
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
HTT huntingtin
HYOU1 hypoxia up-regulated 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
LIAS lipoic acid synthetase
LRPPRC leucine-rich pentatricopeptide repeat containing
MAP1B microtubule-associated protein 1B
METAP2 methionyl aminopeptidase 2
MTAP methylthioadenosine phosphorylase
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NCKAP1 NCK-associated protein 1
NODAL nodal growth differentiation factor
NR4A3 nuclear receptor subfamily 4, group A, member 3
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUP133 nucleoporin 133kDa
PDCD10 programmed cell death 10
PHB2 prohibitin 2
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIKFYVE phosphoinositide kinase, FYVE finger containing
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLG polymerase (DNA directed), gamma
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PRICKLE1 prickle homolog 1 (Drosophila)
PTK2 protein tyrosine kinase 2
QKI QKI, KH domain containing, RNA binding
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RBPJ recombination signal binding protein for immunoglobulin kappa J region
S100A8 S100 calcium binding protein A8
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SF1 splicing factor 1
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SNAI1 snail family zinc finger 1
SUZ12 SUZ12 polycomb repressive complex 2 subunit
T T, brachyury homolog (mouse)
TLN1 talin 1
TPT1 tumor protein, translationally-controlled 1
TRAIP TRAF interacting protein
TRIM33 tripartite motif containing 33
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase
VEGFA vascular endothelial growth factor A
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZBTB17 zinc finger and BTB domain containing 17
ZFR zinc finger RNA binding protein