colon cancer Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A colorectal cancer that is located_in the colon. (Human Disease Ontology, DOID_219)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0003003
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Genes

178 genes associated with the colon cancer phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 1.00059
CALCR calcitonin receptor 0.928309
MALRD1 MAM and LDL receptor class A domain containing 1 0.919744
SLC51A solute carrier family 51, alpha subunit 0.903602
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 0.884602
ZFAND4 zinc finger, AN1-type domain 4 0.870998
CNTNAP2 contactin associated protein-like 2 0.868241
SMAD6 SMAD family member 6 0.855449
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.844241
KLHL32 kelch-like family member 32 0.844241
PTPRJ protein tyrosine phosphatase, receptor type, J 0.844241
TRAPPC9 trafficking protein particle complex 9 0.844241
APP amyloid beta (A4) precursor protein 0.844241
FRMD5 FERM domain containing 5 0.784165
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.778318
EGFR epidermal growth factor receptor 0.772842
C4ORF45 chromosome 4 open reading frame 45 0.772842
AIG1 androgen-induced 1 0.772842
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 0.772842
C20ORF196 chromosome 20 open reading frame 196 0.772842
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.772842
MAP2 microtubule-associated protein 2 0.772842
RYR2 ryanodine receptor 2 (cardiac) 0.772842
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.772842
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.772842
PXDNL peroxidasin-like 0.726078
CHD9 chromodomain helicase DNA binding protein 9 0.726078
ADAMTSL3 ADAMTS-like 3 0.726078
ERBB4 erb-b2 receptor tyrosine kinase 4 0.726078
PCDH9 protocadherin 9 0.726078
NRXN3 neurexin 3 0.726078
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.726078
ELMO1 engulfment and cell motility 1 0.726078
TPK1 thiamin pyrophosphokinase 1 0.726078
ZNF385D zinc finger protein 385D 0.726078
BMPR1B bone morphogenetic protein receptor, type IB 0.726078
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1 0.726078
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.726078
USP45 ubiquitin specific peptidase 45 0.700393
PAX2 paired box 2 0.697013
FAM207A family with sequence similarity 207, member A 0.693745
CCDC67 coiled-coil domain containing 67 0.690584
FGF12 fibroblast growth factor 12 0.690584
LPA lipoprotein, Lp(a) 0.690584
CADM1 cell adhesion molecule 1 0.690584
NRG3 neuregulin 3 0.690584
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.690584
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.690584
ALPK3 alpha-kinase 3 0.690584
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.690584
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 0.690584
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.690584
PTPRD protein tyrosine phosphatase, receptor type, D 0.690584
AOX2P aldehyde oxidase 2 pseudogene 0.690584
FRMD4A FERM domain containing 4A 0.661809
LINC00540 long intergenic non-protein coding RNA 540 0.661809
DCLK1 doublecortin-like kinase 1 0.661809
ARMC8 armadillo repeat containing 8 0.661809
MEMO1 mediator of cell motility 1 0.661809
SOX5 SRY (sex determining region Y)-box 5 0.661809
COL13A1 collagen, type XIII, alpha 1 0.637546
TFEC transcription factor EC 0.637546
ESRRG estrogen-related receptor gamma 0.637546
LDB2 LIM domain binding 2 0.637546
C6ORF89 chromosome 6 open reading frame 89 0.637546
NGEF neuronal guanine nucleotide exchange factor 0.637546
FBLN1 fibulin 1 0.637546
SEZ6L seizure related 6 homolog (mouse)-like 0.637546
ASS1 argininosuccinate synthase 1 0.637546
EIF3E eukaryotic translation initiation factor 3, subunit E 0.637546
SRD5A3 steroid 5 alpha-reductase 3 0.637546
TBC1D22A TBC1 domain family, member 22A 0.620705
PRR16 proline rich 16 0.616892
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 0.616892
DOPEY1 dopey family member 1 0.616892
MACROD1 MACRO domain containing 1 0.616892
MLPH melanophilin 0.616892
LIMCH1 LIM and calponin homology domains 1 0.616892
KIAA1217 KIAA1217 0.616892
KIF13B kinesin family member 13B 0.616892
UMODL1 uromodulin-like 1 0.599122
FAM71F1 family with sequence similarity 71, member F1 0.599122
AKNAD1 AKNA domain containing 1 0.599122
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 0.599122
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 0.599122
CADM2 cell adhesion molecule 2 0.599122
LOC339862 uncharacterized LOC339862 0.599122
PCDH15 protocadherin-related 15 0.599122
SCHIP1 schwannomin interacting protein 1 0.599122
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.599122
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 0.599122
DFNB31 deafness, autosomal recessive 31 0.585507
UBE2W ubiquitin-conjugating enzyme E2W (putative) 0.584275
ELOVL6 ELOVL fatty acid elongase 6 0.584275
SBF2 SET binding factor 2 0.584275
TMEM132D transmembrane protein 132D 0.584275
ASPA aspartoacylase 0.584275
GLIS3 GLIS family zinc finger 3 0.584275
IQCJ IQ motif containing J 0.584275
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.584275
LUZP2 leucine zipper protein 2 0.584275
LOC728755 uncharacterized LOC728755 0.584275
ASTN2 astrotactin 2 0.584275
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 0.584275
LAMA2 laminin, alpha 2 0.584275
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.584275
NTM neurotrimin 0.584275
SAMD3 sterile alpha motif domain containing 3 0.572823
CFAP61 cilia and flagella associated protein 61 0.572823
FRMD6 FERM domain containing 6 0.572823
SGK1 serum/glucocorticoid regulated kinase 1 0.572823
FAM111B family with sequence similarity 111, member B 0.572823
LINC00578 long intergenic non-protein coding RNA 578 0.572823
KIF16B kinesin family member 16B 0.572823
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.572823
RELN reelin 0.572823
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.572823
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.572823
TMEM165 transmembrane protein 165 0.572823
MACROD2 MACRO domain containing 2 0.572823
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.572823
KIAA1456 KIAA1456 0.572823
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 0.572823
NKAIN3 Na+/K+ transporting ATPase interacting 3 0.572823
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.572823
CLOCK clock circadian regulator 0.572823
C6ORF7 chromosome 6 open reading frame 7 0.572823
LYN LYN proto-oncogene, Src family tyrosine kinase 0.572823
SCUBE1 signal peptide, CUB domain, EGF-like 1 0.572823
CNTN5 contactin 5 0.572823
ARHGAP15 Rho GTPase activating protein 15 0.572823
TOX thymocyte selection-associated high mobility group box 0.572823
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 0.572823
CCDC174 coiled-coil domain containing 174 0.572823
PARD3B par-3 family cell polarity regulator beta 0.572823
PELP1 proline, glutamate and leucine rich protein 1 0.572823
FAM189A1 family with sequence similarity 189, member A1 0.572823
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.572823
SPTBN1 spectrin, beta, non-erythrocytic 1 0.572823
LRP5L low density lipoprotein receptor-related protein 5-like 0.572823
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.572823
CSPP1 centrosome and spindle pole associated protein 1 0.572823
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.572823
FGF6 fibroblast growth factor 6 0.572823
CTIF CBP80/20-dependent translation initiation factor 0.572823
CD38 CD38 molecule 0.572823
SLIT1 slit homolog 1 (Drosophila) 0.572823
MAN2B2 mannosidase, alpha, class 2B, member 2 0.572823
C4ORF22 chromosome 4 open reading frame 22 0.572823
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.572823
PADI3 peptidyl arginine deiminase, type III 0.572823
NUP160 nucleoporin 160kDa 0.572823
CLIC5 chloride intracellular channel 5 0.572823
SNAP25 synaptosomal-associated protein, 25kDa 0.572823
PDZRN3 PDZ domain containing ring finger 3 0.572823
MINOS1-NBL1 MINOS1-NBL1 readthrough 0.572823
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.572823
OSBPL1A oxysterol binding protein-like 1A 0.572823
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.572823
SCN3A sodium channel, voltage gated, type III alpha subunit 0.572823
NXPH1 neurexophilin 1 0.572823
DCAF4 DDB1 and CUL4 associated factor 4 0.572823
ATXN1 ataxin 1 0.572823
IRAK3 interleukin-1 receptor-associated kinase 3 0.572823
THADA thyroid adenoma associated 0.572823
FAM163A family with sequence similarity 163, member A 0.572823
PDCL2 phosducin-like 2 0.531556
CHD2 chromodomain helicase DNA binding protein 2 0.528162
APAF1 apoptotic peptidase activating factor 1 0.522136
IKBIP IKBKB interacting protein 0.522136
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.514254
ZFYVE1 zinc finger, FYVE domain containing 1 0.511765
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.509391
TCF3 transcription factor 3 0.50495
CPM carboxypeptidase M 0.496801
CACHD1 cache domain containing 1 0.496801
NBEA neurobeachin 0.476506
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.470822