cobalt chloride-379 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the cobalt chloride-379 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
ADM2 adrenomedullin 2
APOA1 apolipoprotein A-I
ASB13 ankyrin repeat and SOCS box containing 13
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
AZI2 5-azacytidine induced 2
BBIP1 BBSome interacting protein 1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C2CD2L C2CD2-like
CACTIN cactin, spliceosome C complex subunit
CBX6 chromobox homolog 6
CCL2 chemokine (C-C motif) ligand 2
CCNG2 cyclin G2
CEP104 centrosomal protein 104kDa
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CORT cortistatin
CPOX coproporphyrinogen oxidase
DENND5A DENN/MADD domain containing 5A
DHPS deoxyhypusine synthase
DMC1 DNA meiotic recombinase 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DSG3 desmoglein 3
DUS2 dihydrouridine synthase 2
EFNB3 ephrin-B3
EID1 EP300 interacting inhibitor of differentiation 1
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GCAT glycine C-acetyltransferase
HEMK1 HemK methyltransferase family member 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HOXA5 homeobox A5
HPX hemopexin
INSR insulin receptor
IRGQ immunity-related GTPase family, Q
KDM3A lysine (K)-specific demethylase 3A
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KMT2A lysine (K)-specific methyltransferase 2A
KRIT1 KRIT1, ankyrin repeat containing
LEFTY1 left-right determination factor 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LPPR2 lipid phosphate phosphatase-related protein type 2
LUZP1 leucine zipper protein 1
MAML3 mastermind-like 3 (Drosophila)
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MED4 mediator complex subunit 4
MISP mitotic spindle positioning
MKRN1 makorin ring finger protein 1
MOAP1 modulator of apoptosis 1
MT1E metallothionein 1E
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NDRG3 NDRG family member 3
NUPL1 nucleoporin like 1
NXPH3 neurexophilin 3
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PARD3 par-3 family cell polarity regulator
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PITPNA phosphatidylinositol transfer protein, alpha
PLK4 polo-like kinase 4
PPME1 protein phosphatase methylesterase 1
PSG9 pregnancy specific beta-1-glycoprotein 9
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTP4A2 protein tyrosine phosphatase type IVA, member 2
R3HCC1 R3H domain and coiled-coil containing 1
RAD51D RAD51 paralog D
RASL10A RAS-like, family 10, member A
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RGS2 regulator of G-protein signaling 2
SATB1 SATB homeobox 1
SELPLG selectin P ligand
SGK2 serum/glucocorticoid regulated kinase 2
SGSH N-sulfoglucosamine sulfohydrolase
SKAP2 src kinase associated phosphoprotein 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMG7 SMG7 nonsense mediated mRNA decay factor
SOD2 superoxide dismutase 2, mitochondrial
SPP1 secreted phosphoprotein 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
TEX13B testis expressed 13B
TGM2 transglutaminase 2
TMEM127 transmembrane protein 127
TMEM209 transmembrane protein 209
TMEM70 transmembrane protein 70
TNK2 tyrosine kinase, non-receptor, 2
TOP3B topoisomerase (DNA) III beta
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
TSSK2 testis-specific serine kinase 2
TUBA4B tubulin, alpha 4b
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USF2 upstream transcription factor 2, c-fos interacting
VAC14 Vac14 homolog (S. cerevisiae)
VGLL4 vestigial-like family member 4
ZBTB43 zinc finger and BTB domain containing 43
ZNF609 zinc finger protein 609
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACP6 acid phosphatase 6, lysophosphatidic
ACVRL1 activin A receptor type II-like 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AOAH acyloxyacyl hydrolase (neutrophil)
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APOD apolipoprotein D
ARHGAP10 Rho GTPase activating protein 10
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATOX1 antioxidant 1 copper chaperone
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BACE2 beta-site APP-cleaving enzyme 2
BATF basic leucine zipper transcription factor, ATF-like
BHMT betaine--homocysteine S-methyltransferase
BRAF B-Raf proto-oncogene, serine/threonine kinase
C2 complement component 2
C22ORF29 chromosome 22 open reading frame 29
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCR4 chemokine (C-C motif) receptor 4
CD177 CD177 molecule
CECR1 cat eye syndrome chromosome region, candidate 1
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLCF1 cardiotrophin-like cytokine factor 1
CLDN9 claudin 9
CLK3 CDC-like kinase 3
CNTD2 cyclin N-terminal domain containing 2
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DENND4C DENN/MADD domain containing 4C
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DMTN dematin actin binding protein
DUSP13 dual specificity phosphatase 13
ECM1 extracellular matrix protein 1
ELP4 elongator acetyltransferase complex subunit 4
ENO3 enolase 3 (beta, muscle)
ERCC4 excision repair cross-complementation group 4
ERCC8 excision repair cross-complementation group 8
FCHO1 FCH domain only 1
FSCN3 fascin actin-bundling protein 3, testicular
GIPC1 GIPC PDZ domain containing family, member 1
GPA33 glycoprotein A33 (transmembrane)
GPR15 G protein-coupled receptor 15
GRHL2 grainyhead-like 2 (Drosophila)
GSTA4 glutathione S-transferase alpha 4
HAND1 heart and neural crest derivatives expressed 1
HBBP1 hemoglobin, beta pseudogene 1
HDAC11 histone deacetylase 11
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL22 interleukin 22
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INTS9 integrator complex subunit 9
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LINC00574 long intergenic non-protein coding RNA 574
MB myoglobin
MRPL4 mitochondrial ribosomal protein L4
MYBBP1A MYB binding protein (P160) 1a
MYL1 myosin, light chain 1, alkali; skeletal, fast
N4BP3 NEDD4 binding protein 3
NEO1 neogenin 1
NOL6 nucleolar protein 6 (RNA-associated)
NPAP1 nuclear pore associated protein 1
NTHL1 nth endonuclease III-like 1 (E. coli)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCSK7 proprotein convertase subtilisin/kexin type 7
PELP1 proline, glutamate and leucine rich protein 1
PHKG2 phosphorylase kinase, gamma 2 (testis)
PICK1 protein interacting with PRKCA 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLD2 phospholipase D2
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PPOX protoporphyrinogen oxidase
PRKCE protein kinase C, epsilon
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RFTN1 raftlin, lipid raft linker 1
RLBP1 retinaldehyde binding protein 1
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SIK1 salt-inducible kinase 1
SLC26A10 solute carrier family 26, member 10
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SOX21 SRY (sex determining region Y)-box 21
SPDL1 spindle apparatus coiled-coil protein 1
ST5 suppression of tumorigenicity 5
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TGFB3 transforming growth factor, beta 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THRB thyroid hormone receptor, beta
TRAPPC12 trafficking protein particle complex 12
TRIM16 tripartite motif containing 16
URGCP upregulator of cell proliferation
VIPR1 vasoactive intestinal peptide receptor 1
ZBTB16 zinc finger and BTB domain containing 16
ZNF550 zinc finger protein 550
ZNF573 zinc finger protein 573