clofibrate-263 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the clofibrate-263 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAP1 ArfGAP with dual PH domains 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AP3D1 adaptor-related protein complex 3, delta 1 subunit
ARFRP1 ADP-ribosylation factor related protein 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARSF arylsulfatase F
ATM ATM serine/threonine kinase
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATXN2L ataxin 2-like
BCAM basal cell adhesion molecule (Lutheran blood group)
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CARD9 caspase recruitment domain family, member 9
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCNK cyclin K
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DCAF8 DDB1 and CUL4 associated factor 8
DCSTAMP dendrocyte expressed seven transmembrane protein
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DMWD dystrophia myotonica, WD repeat containing
DNASE1L2 deoxyribonuclease I-like 2
DRP2 dystrophin related protein 2
ECE1 endothelin converting enzyme 1
EFNB3 ephrin-B3
EHD1 EH-domain containing 1
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ENG endoglin
ESR1 estrogen receptor 1
FAM107A family with sequence similarity 107, member A
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FNDC3A fibronectin type III domain containing 3A
FOSL2 FOS-like antigen 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GYPC glycophorin C (Gerbich blood group)
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HDC histidine decarboxylase
HEXA hexosaminidase A (alpha polypeptide)
HLF hepatic leukemia factor
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IL15RA interleukin 15 receptor, alpha
IL21R interleukin 21 receptor
IL5RA interleukin 5 receptor, alpha
KALRN kalirin, RhoGEF kinase
KHSRP KH-type splicing regulatory protein
KIF25 kinesin family member 25
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KRT6B keratin 6B, type II
L1CAM L1 cell adhesion molecule
LCN2 lipocalin 2
LHB luteinizing hormone beta polypeptide
LINC00652 long intergenic non-protein coding RNA 652
LPPR2 lipid phosphate phosphatase-related protein type 2
MALL mal, T-cell differentiation protein-like
MAP1A microtubule-associated protein 1A
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MED18 mediator complex subunit 18
MEFV Mediterranean fever
MLXIP MLX interacting protein
MLXIPL MLX interacting protein-like
MPPE1 metallophosphoesterase 1
MTERF4 mitochondrial transcription termination factor 4
MYBPC3 myosin binding protein C, cardiac
NBL1 neuroblastoma 1, DAN family BMP antagonist
NF1 neurofibromin 1
NNAT neuronatin
NOX1 NADPH oxidase 1
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLXNB3 plexin B3
PPP1R37 protein phosphatase 1, regulatory subunit 37
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RPLP2 ribosomal protein, large, P2
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SMAD3 SMAD family member 3
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
TAOK2 TAO kinase 2
TLN2 talin 2
TNK2 tyrosine kinase, non-receptor, 2
TP53I11 tumor protein p53 inducible protein 11
TXNL4A thioredoxin-like 4A
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VRK3 vaccinia related kinase 3
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF318 zinc finger protein 318

decreased expression

Symbol Name
ACTN4 actinin, alpha 4
AHR aryl hydrocarbon receptor
ANGPT4 angiopoietin 4
AQP8 aquaporin 8
ASCC1 activating signal cointegrator 1 complex subunit 1
ASGR2 asialoglycoprotein receptor 2
ASIP agouti signaling protein
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C19ORF57 chromosome 19 open reading frame 57
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CCDC94 coiled-coil domain containing 94
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CENPQ centromere protein Q
CHD2 chromodomain helicase DNA binding protein 2
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DGAT1 diacylglycerol O-acyltransferase 1
DGKD diacylglycerol kinase, delta 130kDa
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DSG2 desmoglein 2
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
FCHSD2 FCH and double SH3 domains 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FTCD formimidoyltransferase cyclodeaminase
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GCM1 glial cells missing homolog 1 (Drosophila)
GDF5 growth differentiation factor 5
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPR19 G protein-coupled receptor 19
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
ICK intestinal cell (MAK-like) kinase
IFI27 interferon, alpha-inducible protein 27
IL10RA interleukin 10 receptor, alpha
IL13 interleukin 13
IL36RN interleukin 36 receptor antagonist
IRGC immunity-related GTPase family, cinema
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
JMJD4 jumonji domain containing 4
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KDM8 lysine (K)-specific demethylase 8
KIFAP3 kinesin-associated protein 3
LBR lamin B receptor
LIN7B lin-7 homolog B (C. elegans)
LRP4 low density lipoprotein receptor-related protein 4
MBIP MAP3K12 binding inhibitory protein 1
MFGE8 milk fat globule-EGF factor 8 protein
MIR22HG MIR22 host gene
MMP3 matrix metallopeptidase 3
MUC2 mucin 2, oligomeric mucus/gel-forming
MVP major vault protein
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NPPB natriuretic peptide B
NPY1R neuropeptide Y receptor Y1
PARG poly (ADP-ribose) glycohydrolase
PCF11 PCF11 cleavage and polyadenylation factor subunit
PGBD5 piggyBac transposable element derived 5
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
POGLUT1 protein O-glucosyltransferase 1
PPARG peroxisome proliferator-activated receptor gamma
PRDM14 PR domain containing 14
PTK6 protein tyrosine kinase 6
RIMBP2 RIMS binding protein 2
RNF141 ring finger protein 141
RPL10L ribosomal protein L10-like
RPL23AP7 ribosomal protein L23a pseudogene 7
SCARA3 scavenger receptor class A, member 3
SGCE sarcoglycan, epsilon
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIL1 SIL1 nucleotide exchange factor
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPRR3 small proline-rich protein 3
STAT5A signal transducer and activator of transcription 5A
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TMEM165 transmembrane protein 165
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TREM1 triggering receptor expressed on myeloid cells 1
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
USP18 ubiquitin specific peptidase 18
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
WT1-AS WT1 antisense RNA
ZC4H2 zinc finger, C4H2 domain containing
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZDHHC8P1 zinc finger, DHHC-type containing 8 pseudogene 1
ZNF107 zinc finger protein 107
ZNF134 zinc finger protein 134
ZNF140 zinc finger protein 140
ZNF180 zinc finger protein 180
ZNF492 zinc finger protein 492
ZNF516 zinc finger protein 516
ZNF639 zinc finger protein 639
ZNF668 zinc finger protein 668
ZNF701 zinc finger protein 701