clidinium bromide-3476 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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192 genes differentially expressed following the clidinium bromide-3476 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL4C ADP-ribosylation factor-like 4C
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BRCA1 breast cancer 1, early onset
CA5B carbonic anhydrase VB, mitochondrial
CBX8 chromobox homolog 8
CCDC186 coiled-coil domain containing 186
CD1E CD1e molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CLDN15 claudin 15
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CTSE cathepsin E
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DOK4 docking protein 4
DVL2 dishevelled segment polarity protein 2
EMID1 EMI domain containing 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ERCC2 excision repair cross-complementation group 2
ERCC4 excision repair cross-complementation group 4
FKBP8 FK506 binding protein 8, 38kDa
FOXN3 forkhead box N3
FPGS folylpolyglutamate synthase
HFE hemochromatosis
HIST1H1D histone cluster 1, H1d
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGHA1 immunoglobulin heavy constant alpha 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KAZN kazrin, periplakin interacting protein
KLHL24 kelch-like family member 24
KPNA5 karyopherin alpha 5 (importin alpha 6)
LAMB1 laminin, beta 1
LPP LIM domain containing preferred translocation partner in lipoma
MAP4 microtubule-associated protein 4
MARK4 MAP/microtubule affinity-regulating kinase 4
MCF2L MCF.2 cell line derived transforming sequence-like
MED16 mediator complex subunit 16
MED18 mediator complex subunit 18
MEFV Mediterranean fever
MTA2 metastasis associated 1 family, member 2
MTERF4 mitochondrial transcription termination factor 4
MTRF1L mitochondrial translational release factor 1-like
MYL10 myosin, light chain 10, regulatory
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKX3-2 NK3 homeobox 2
NME5 NME/NM23 family member 5
NMT1 N-myristoyltransferase 1
OSGIN1 oxidative stress induced growth inhibitor 1
PCDHGB5 protocadherin gamma subfamily B, 5
PITX1 paired-like homeodomain 1
PLLP plasmolipin
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PODXL2 podocalyxin-like 2
POFUT1 protein O-fucosyltransferase 1
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTPRS protein tyrosine phosphatase, receptor type, S
PVR poliovirus receptor
PVRL3 poliovirus receptor-related 3
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RER1 retention in endoplasmic reticulum sorting receptor 1
RGS12 regulator of G-protein signaling 12
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIN2 Ras and Rab interactor 2
RTEL1 regulator of telomere elongation helicase 1
RUFY3 RUN and FYVE domain containing 3
S100A7 S100 calcium binding protein A7
SEC63 SEC63 homolog (S. cerevisiae)
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMAD3 SMAD family member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC1A structural maintenance of chromosomes 1A
SOAT2 sterol O-acyltransferase 2
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SYN3 synapsin III
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAPBP TAP binding protein (tapasin)
TGFB2 transforming growth factor, beta 2
TLK1 tousled-like kinase 1
TSC22D2 TSC22 domain family, member 2
TTC9 tetratricopeptide repeat domain 9
USB1 U6 snRNA biogenesis 1
USP36 ubiquitin specific peptidase 36
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZHX3 zinc fingers and homeoboxes 3
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF329 zinc finger protein 329
ZNF34 zinc finger protein 34
ZNF609 zinc finger protein 609
ZNF862 zinc finger protein 862
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADM adrenomedullin
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
ATF3 activating transcription factor 3
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BBS1 Bardet-Biedl syndrome 1
C14ORF93 chromosome 14 open reading frame 93
C2ORF44 chromosome 2 open reading frame 44
CAMTA2 calmodulin binding transcription activator 2
CCDC69 coiled-coil domain containing 69
CDK3 cyclin-dependent kinase 3
CFD complement factor D (adipsin)
CGREF1 cell growth regulator with EF-hand domain 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIC capicua transcriptional repressor
CNGB3 cyclic nucleotide gated channel beta 3
CRYBG3 beta-gamma crystallin domain containing 3
CUL9 cullin 9
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DOC2A double C2-like domains, alpha
DSCAM Down syndrome cell adhesion molecule
FAM131A family with sequence similarity 131, member A
FAM86C1 family with sequence similarity 86, member C1
FAR2 fatty acyl CoA reductase 2
FBRS fibrosin
FMOD fibromodulin
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH3 G patch domain containing 3
GRB7 growth factor receptor-bound protein 7
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HSPA1L heat shock 70kDa protein 1-like
IPO8 importin 8
ITPKB inositol-trisphosphate 3-kinase B
ITPKC inositol-trisphosphate 3-kinase C
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0319L KIAA0319-like
KLC2 kinesin light chain 2
LIN7B lin-7 homolog B (C. elegans)
LOC730101 uncharacterized LOC730101
LPAR4 lysophosphatidic acid receptor 4
LYPLA2P1 lysophospholipase II pseudogene 1
LYRM9 LYR motif containing 9
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAMLD1 mastermind-like domain containing 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
NEK11 NIMA-related kinase 11
NIPAL2 NIPA-like domain containing 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NT5E 5'-nucleotidase, ecto (CD73)
OSMR oncostatin M receptor
PADI2 peptidyl arginine deiminase, type II
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G3 phospholipase A2, group III
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PPOX protoporphyrinogen oxidase
PPT2 palmitoyl-protein thioesterase 2
PRSS16 protease, serine, 16 (thymus)
R3HCC1L R3H domain and coiled-coil containing 1-like
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHOG ras homolog family member G
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIBC2 RIB43A domain with coiled-coils 2
RNF126P1 ring finger protein 126 pseudogene 1
RWDD3 RWD domain containing 3
SAYSD1 SAYSVFN motif domain containing 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIRT6 sirtuin 6
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC22A14 solute carrier family 22, member 14
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMG9 SMG9 nonsense mediated mRNA decay factor
SND1-IT1 SND1 intronic transcript 1
SPATA2L spermatogenesis associated 2-like
TFB1M transcription factor B1, mitochondrial
THBS3 thrombospondin 3
THOP1 thimet oligopeptidase 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMC5 transmembrane channel-like 5
TRAIP TRAF interacting protein
TRAPPC11 trafficking protein particle complex 11
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VASH2 vasohibin 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF211 zinc finger protein 211
ZNF227 zinc finger protein 227
ZNF250 zinc finger protein 250
ZNF480 zinc finger protein 480