cleft lip Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Similar Terms
Downloads & Tools

Genes

365 genes co-occuring with the disease cleft lip in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TMEM54 transmembrane protein 54 3.32113
IRF6 interferon regulatory factor 6 2.64263
MSX1 msh homeobox 1 2.3262
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 2.00102
TGFB3 transforming growth factor, beta 3 1.99872
TGFA transforming growth factor, alpha 1.9755
WNT9B wingless-type MMTV integration site family, member 9B 1.9122
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 1.78804
TP63 tumor protein p63 1.70451
PHF8 PHD finger protein 8 1.6986
ARHGAP29 Rho GTPase activating protein 29 1.66961
CLPTM1 cleft lip and palate associated transmembrane protein 1 1.60994
TBX10 T-box 10 1.60502
NANS N-acetylneuraminic acid synthase 1.60368
BCL3 B-cell CLL/lymphoma 3 1.60279
VAX1 ventral anterior homeobox 1 1.5876
CLPTM1L CLPTM1-like 1.53172
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.51369
BMP4 bone morphogenetic protein 4 1.49657
TBX22 T-box 22 1.4733
FOXE1 forkhead box E1 1.45485
WNT3 wingless-type MMTV integration site family, member 3 1.45397
PAX9 paired box 9 1.39826
BHMT2 betaine--homocysteine S-methyltransferase 2 1.39608
B3GALTL beta 1,3-galactosyltransferase-like 1.31187
SHH sonic hedgehog 1.30095
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 1.28785
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.26168
FGFR1 fibroblast growth factor receptor 1 1.26124
GLI2 GLI family zinc finger 2 1.22172
WNT8A wingless-type MMTV integration site family, member 8A 1.21522
RARA retinoic acid receptor, alpha 1.21045
CENPL centromere protein L 1.20483
VAX2 ventral anterior homeobox 2 1.19229
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 1.18927
F13A1 coagulation factor XIII, A1 polypeptide 1.18582
PRSS23 protease, serine, 23 1.18066
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 1.16949
ZIC2 Zic family member 2 1.16778
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.16649
FGF10 fibroblast growth factor 10 1.15496
CHD7 chromodomain helicase DNA binding protein 7 1.15453
DCAF4L2 DDB1 and CUL4 associated factor 4-like 2 1.14348
ZNF714 zinc finger protein 714 1.14348
C9ORF156 chromosome 9 open reading frame 156 1.14348
ZNF431 zinc finger protein 431 1.14348
FGF8 fibroblast growth factor 8 (androgen-induced) 1.13839
PTER phosphotriesterase related 1.13797
FANCL Fanconi anemia, complementation group L 1.12277
SIX3 SIX homeobox 3 1.09671
MKX mohawk homeobox 1.03325
SMCP sperm mitochondria-associated cysteine-rich protein 1.01638
SKP1 S-phase kinase-associated protein 1 1.0071
DLX5 distal-less homeobox 5 0.994017
WNT11 wingless-type MMTV integration site family, member 11 0.989379
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 0.988957
PPP4R2 protein phosphatase 4, regulatory subunit 2 0.982215
MYL4 myosin, light chain 4, alkali; atrial, embryonic 0.966663
DLX3 distal-less homeobox 3 0.95996
BHMT betaine--homocysteine S-methyltransferase 0.944938
NOTCH1 notch 1 0.94369
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 0.935385
CHDH choline dehydrogenase 0.9238
GLB1L2 galactosidase, beta 1-like 2 0.916375
OFD1 oral-facial-digital syndrome 1 0.913492
PDGFC platelet derived growth factor C 0.908553
FBXO28 F-box protein 28 0.906086
PVRL4 poliovirus receptor-related 4 0.899514
SATB2 SATB homeobox 2 0.88516
CRISPLD1 cysteine-rich secretory protein LCCL domain containing 1 0.879424
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 0.877376
TBX1 T-box 1 0.865093
ANOS1 anosmin 1 0.864684
APOC2 apolipoprotein C-II 0.863456
MSX2 msh homeobox 2 0.861818
BMP2 bone morphogenetic protein 2 0.858952
FGF12 fibroblast growth factor 12 0.851992
AXIN2 axin 2 0.849536
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.846259
LHX8 LIM homeobox 8 0.842163
PROK2 prokineticin 2 0.840934
GPR27 G protein-coupled receptor 27 0.840115
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.824538
SLC39A3 solute carrier family 39 (zinc transporter), member 3 0.822897
PROKR2 prokineticin receptor 2 0.821667
PTCH1 patched 1 0.818385
JAG2 jagged 2 0.80977
SUMO1 small ubiquitin-like modifier 1 0.80977
FGFR2 fibroblast growth factor receptor 2 0.806077
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 0.801154
BSPRY B-box and SPRY domain containing 0.797462
CNTNAP3 contactin associated protein-like 3 0.795821
PERP PERP, TP53 apoptosis effector 0.795002
STK32B serine/threonine kinase 32B 0.780251
PAX7 paired box 7 0.779841
FGF3 fibroblast growth factor 3 0.772479
EFNB1 ephrin-B1 0.763086
WNT3A wingless-type MMTV integration site family, member 3A 0.762271
ROR2 receptor tyrosine kinase-like orphan receptor 2 0.757786
DLX6 distal-less homeobox 6 0.749644
MYH9 myosin, heavy chain 9, non-muscle 0.746391
TERT telomerase reverse transcriptase 0.745985
PVR poliovirus receptor 0.743141
SLC25A43 solute carrier family 25, member 43 0.731786
DUX4L9 double homeobox 4 like 9 0.72612
DUX4L4 double homeobox 4 like 4 0.72612
GOSR2 golgi SNAP receptor complex member 2 0.723694
DPF3 D4, zinc and double PHD fingers, family 3 0.717635
LIG3 ligase III, DNA, ATP-dependent 0.716425
SYNJ2 synaptojanin 2 0.71078
EN2 engrailed homeobox 2 0.709975
HMX1 H6 family homeobox 1 0.701526
ZNF385B zinc finger protein 385B 0.699919
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.693098
RYK receptor-like tyrosine kinase 0.686291
SLC19A1 solute carrier family 19 (folate transporter), member 1 0.686291
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) 0.684692
TDGF1 teratocarcinoma-derived growth factor 1 0.684292
ZNF189 zinc finger protein 189 0.683892
IK IK cytokine, down-regulator of HLA II 0.676706
SALL3 spalt-like transcription factor 3 0.673518
TSHZ1 teashirt zinc finger homeobox 1 0.670732
ADAMTSL1 ADAMTS-like 1 0.66755
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.66199
C1ORF174 chromosome 1 open reading frame 174 0.658026
COLEC11 collectin sub-family member 11 0.65565
WNT5A wingless-type MMTV integration site family, member 5A 0.648928
PDE4DIP phosphodiesterase 4D interacting protein 0.643404
SP8 Sp8 transcription factor 0.642615
DMKN dermokine 0.642221
LAMC3 laminin, gamma 3 0.641433
XKR6 XK, Kell blood group complex subunit-related family, member 6 0.638282
CPM carboxypeptidase M 0.637495
FGF9 fibroblast growth factor 9 0.635921
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 0.635528
CLDN6 claudin 6 0.632384
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.625711
DMGDH dimethylglycine dehydrogenase 0.623359
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.619442
PAX3 paired box 3 0.608494
PSPC1 paraspeckle component 1 0.605372
CDC27 cell division cycle 27 0.60303
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 0.60147
TMCC1 transmembrane and coiled-coil domain family 1 0.597961
BMPR1B bone morphogenetic protein receptor, type IB 0.597571
MNX1 motor neuron and pancreas homeobox 1 0.596402
EVC2 Ellis van Creveld syndrome 2 0.593674
TCN2 transcobalamin II 0.591727
SAE1 SUMO1 activating enzyme subunit 1 0.591337
HEMGN hemogen 0.589779
SLC39A1 solute carrier family 39 (zinc transporter), member 1 0.587444
CLPS colipase, pancreatic 0.584719
KPTN kaptin (actin binding protein) 0.578494
SGOL1 shugoshin-like 1 (S. pombe) 0.574605
BARX1 BARX homeobox 1 0.574217
FAM120C family with sequence similarity 120C 0.572273
DOLK dolichol kinase 0.56722
TNN tenascin N 0.557897
FOLR1 folate receptor 1 (adult) 0.556732
FGF18 fibroblast growth factor 18 0.545868
FILIP1L filamin A interacting protein 1-like 0.540055
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 0.534635
FGF1 fibroblast growth factor 1 (acidic) 0.530768
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.52343
OR2Y1 olfactory receptor, family 2, subfamily Y, member 1 0.520731
RUNX2 runt-related transcription factor 2 0.520731
GDF1 growth differentiation factor 1 0.516879
ETNK1 ethanolamine kinase 1 0.507273
GRHL3 grainyhead-like 3 (Drosophila) 0.499614
CRHR1 corticotropin releasing hormone receptor 1 0.498467
LEFTY2 left-right determination factor 2 0.49274
TGFBR3 transforming growth factor, beta receptor III 0.487788
SLC30A5 solute carrier family 30 (zinc transporter), member 5 0.483985
NCK2 NCK adaptor protein 2 0.482844
NOG noggin 0.482464
MYH14 myosin, heavy chain 14, non-muscle 0.480566
ALX3 ALX homeobox 3 0.479047
MCM8 minichromosome maintenance complex component 8 0.47374
DLG3 discs, large homolog 3 (Drosophila) 0.473361
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.472604
TMCO1 transmembrane and coiled-coil domains 1 0.468819
GREM1 gremlin 1, DAN family BMP antagonist 0.465038
EVC Ellis van Creveld protein 0.463905
GNRHR gonadotropin-releasing hormone receptor 0.463527
PRKG2 protein kinase, cGMP-dependent, type II 0.462772
GRID2 glutamate receptor, ionotropic, delta 2 0.450701
ANGPTL1 angiopoietin-like 1 0.446935
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.445052
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) 0.443547
KAT6B K(lysine) acetyltransferase 6B 0.440914
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.440162
EPHB3 EPH receptor B3 0.439034
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 0.434899
MID1 midline 1 0.433772
WDR35 WD repeat domain 35 0.430768
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 0.430393
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.428516
MACROD2 MACRO domain containing 2 0.42814
TGFB2 transforming growth factor, beta 2 0.427765
IFT80 intraflagellar transport 80 0.42739
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 0.424389
NEK1 NIMA-related kinase 1 0.424389
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 0.421765
COL11A2 collagen, type XI, alpha 2 0.419892
COL11A2P1 collagen, type XI, alpha 2 pseudogene 1 0.419892
DNM3 dynamin 3 0.417644
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.416521
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.416521
KDM2B lysine (K)-specific demethylase 2B 0.415398
FBXO8 F-box protein 8 0.413527
SLC30A4 solute carrier family 30 (zinc transporter), member 4 0.413527
RYBP RING1 and YY1 binding protein 0.411283
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.410535
ATM ATM serine/threonine kinase 0.408292
CFC1 cripto, FRL-1, cryptic family 1 0.406051
TIMP2 TIMP metallopeptidase inhibitor 2 0.403064
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.401572
KMT2B lysine (K)-specific methyltransferase 2B 0.399334
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.395608
CBS cystathionine-beta-synthase 0.395235
WNK3 WNK lysine deficient protein kinase 3 0.391141
FGF14 fibroblast growth factor 14 0.390397
JARID2 jumonji, AT rich interactive domain 2 0.389653
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.387794
CCDC26 CCDC26 long non-coding RNA 0.387051
SNAP91 synaptosomal-associated protein, 91kDa 0.386679
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.377031
GLYAT glycine-N-acyltransferase 0.37629
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 0.374809
HOXA1 homeobox A1 0.373698
LEFTY1 left-right determination factor 1 0.372958
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.371477
GSTM1 glutathione S-transferase mu 1 0.36704
TACC1 transforming, acidic coiled-coil containing protein 1 0.365932
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene 0.364824
G0S2 G0/G1 switch 2 0.363716
MYH1 myosin, heavy chain 1, skeletal muscle, adult 0.360395
ITGB5 integrin, beta 5 0.359289
MMP24 matrix metallopeptidase 24 (membrane-inserted) 0.357446
HOXA2 homeobox A2 0.356341
MEIS2 Meis homeobox 2 0.354131
BAG4 BCL2-associated athanogene 4 0.353395
WNT10A wingless-type MMTV integration site family, member 10A 0.353027
ACVR1C activin A receptor, type IC 0.353027
POMT1 protein-O-mannosyltransferase 1 0.351923
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 0.349717
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase 0.346409
FGA fibrinogen alpha chain 0.346409
PIAS2 protein inhibitor of activated STAT, 2 0.341639
FAF1 Fas (TNFRSF6) associated factor 1 0.340906
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.335778
NSF N-ethylmaleimide-sensitive factor 0.333949
NODAL nodal growth differentiation factor 0.333218
NOVA2 neuro-oncological ventral antigen 2 0.33066
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.328469
PAX1 paired box 1 0.325187
COL8A1 collagen, type VIII, alpha 1 0.324823
HOXB5 homeobox B5 0.323365
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.321909
FRK fyn-related Src family tyrosine kinase 0.321909
ZIC3 Zic family member 3 0.318272
FOXH1 forkhead box H1 0.312827
A1BG alpha-1-B glycoprotein 0.312464
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 0.312102
PRIMA1 proline rich membrane anchor 1 0.311014
EPGN epithelial mitogen 0.310652
FGFBP1 fibroblast growth factor binding protein 1 0.309566
HMOX2 heme oxygenase 2 0.308842
KISS1R KISS1 receptor 0.30848
FGFR3 fibroblast growth factor receptor 3 0.305587
AFP alpha-fetoprotein 0.304503
CSHL1 chorionic somatomammotropin hormone-like 1 0.303059
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.302698
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G 0.294772
BMPR1A bone morphogenetic protein receptor, type IA 0.294053
SPON1 spondin 1, extracellular matrix protein 0.293334
NRXN3 neurexin 3 0.286519
SLC31A1 solute carrier family 31 (copper transporter), member 1 0.286519
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.284728
TOR1A torsin family 1, member A (torsin A) 0.284371
DLX4 distal-less homeobox 4 0.275089
AMELY amelogenin, Y-linked 0.274021
SULT4A1 sulfotransferase family 4A, member 1 0.272597
ASS1 argininosuccinate synthase 1 0.27153
USH1G Usher syndrome 1G (autosomal recessive) 0.269753
WNT6 wingless-type MMTV integration site family, member 6 0.269398
GLE1 GLE1 RNA export mediator 0.26514
SCNN1D sodium channel, non voltage gated 1 delta subunit 0.264431
SPEN spen family transcriptional repressor 0.264077
SKI SKI proto-oncogene 0.260538
AMELX amelogenin, X-linked 0.260538
NCOA1 nuclear receptor coactivator 1 0.25877
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.257358
THADA thyroid adenoma associated 0.252422
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.243645
LHX4 LIM homeobox 4 0.241895
GSTTP1 glutathione S-transferase theta pseudogene 1 0.241546
GSTT1 glutathione S-transferase theta 1 0.241546
CHKA choline kinase alpha 0.241196
MALL mal, T-cell differentiation protein-like 0.23945
EPHX2 epoxide hydrolase 2, cytoplasmic 0.238403
WNT1 wingless-type MMTV integration site family, member 1 0.238054
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.237357
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 0.235268
BPIFA1 BPI fold containing family A, member 1 0.235268
WDR5 WD repeat domain 5 0.234573
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 0.232489
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.231448
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.230409
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 0.230409
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.22937
MMP28 matrix metallopeptidase 28 0.228333
TAC3 tachykinin 3 0.227988
FGF20 fibroblast growth factor 20 0.227297
HRAS Harvey rat sarcoma viral oncogene homolog 0.226952
LEF1 lymphoid enhancer-binding factor 1 0.226607
AXIN1 axin 1 0.225917
MACF1 microtubule-actin crosslinking factor 1 0.224884
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 0.223165
MIB2 mindbomb E3 ubiquitin protein ligase 2 0.222822
RPL11 ribosomal protein L11 0.215653
BMP3 bone morphogenetic protein 3 0.215314
RPL5 ribosomal protein L5 0.214297
FGF4 fibroblast growth factor 4 0.213959
TGFB1 transforming growth factor, beta 1 0.212608
DVL2 dishevelled segment polarity protein 2 0.210589
IHH indian hedgehog 0.210589
CSMD1 CUB and Sushi multiple domains 1 0.209583
BMP5 bone morphogenetic protein 5 0.208245
SPRY2 sprouty homolog 2 (Drosophila) 0.205916
GDF6 growth differentiation factor 6 0.205585
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.202946
IRF5 interferon regulatory factor 5 0.201635
PODXL podocalyxin-like 0.200331
COL9A1 collagen, type IX, alpha 1 0.200006
MPDU1 mannose-P-dolichol utilization defect 1 0.197742
PIAS1 protein inhibitor of activated STAT, 1 0.196459
RPS14 ribosomal protein S14 0.194865
TWIST2 twist family bHLH transcription factor 2 0.192031
PEMT phosphatidylethanolamine N-methyltransferase 0.190168
IRF9 interferon regulatory factor 9 0.188938
ACVR1B activin A receptor, type IB 0.187415
STOM stomatin 0.185612
NEK2 NIMA-related kinase 2 0.185313
BMP15 bone morphogenetic protein 15 0.183835
CTNNBIP1 catenin, beta interacting protein 1 0.180084
COL4A2 collagen, type IV, alpha 2 0.178126
EDN1 endothelin 1 0.176757
MOGS mannosyl-oligosaccharide glucosidase 0.175947
DYNLRB1 dynein, light chain, roadblock-type 1 0.173314
C1QBP complement component 1, q subcomponent binding protein 0.173314
SUMO3 small ubiquitin-like modifier 3 0.173314
EPHA3 EPH receptor A3 0.172799
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.172038
SLURP1 secreted LY6/PLAUR domain containing 1 0.168148
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.166319
GSK3B glycogen synthase kinase 3 beta 0.164571
SUMO2 small ubiquitin-like modifier 2 0.162707
PER1 period circadian clock 1 0.162306
MMP3 matrix metallopeptidase 3 0.162109
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.161716
SRGN serglycin 0.160574
RGN regucalcin 0.15948
ETV5 ets variant 5 0.158951
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.157765