cicloheximide-6220 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the cicloheximide-6220 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AMOTL2 angiomotin like 2
ARID4A AT rich interactive domain 4A (RBP1-like)
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCOR BCL6 corepressor
BIRC3 baculoviral IAP repeat containing 3
BTN2A1 butyrophilin, subfamily 2, member A1
C7ORF43 chromosome 7 open reading frame 43
CCNO cyclin O
CDK20 cyclin-dependent kinase 20
CDKN2AIP CDKN2A interacting protein
CRYGC crystallin, gamma C
CSF1 colony stimulating factor 1 (macrophage)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DLX2 distal-less homeobox 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DSC2 desmocollin 2
DUSP1 dual specificity phosphatase 1
EFNA1 ephrin-A1
EGR1 early growth response 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPHA2 EPH receptor A2
FLRT3 fibronectin leucine rich transmembrane protein 3
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GAS7 growth arrest-specific 7
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
H1F0 H1 histone family, member 0
H2BFS H2B histone family, member S (pseudogene)
HEG1 heart development protein with EGF-like domains 1
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H2AC histone cluster 1, H2ac
HIST1H2AG histone cluster 1, H2ag
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BH histone cluster 1, H2bh
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BK histone cluster 1, H2bk
HIST1H3B histone cluster 1, H3b
HIST1H3H histone cluster 1, H3h
HIST1H4C histone cluster 1, H4c
HIST1H4H histone cluster 1, H4h
HIST2H2BE histone cluster 2, H2be
HIST3H2A histone cluster 3, H2a
HOXC13 homeobox C13
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER2 immediate early response 2
INTS6 integrator complex subunit 6
IRF1 interferon regulatory factor 1
JUN jun proto-oncogene
KLF10 Kruppel-like factor 10
LYST lysosomal trafficking regulator
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MT1F metallothionein 1F
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OVOL1 ovo-like zinc finger 1
OVOL2 ovo-like zinc finger 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLAA phospholipase A2-activating protein
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PSPC1 paraspeckle component 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RIOK3 RIO kinase 3
RNF19B ring finger protein 19B
SERTAD2 SERTA domain containing 2
SERTAD3 SERTA domain containing 3
SLC16A6 solute carrier family 16, member 6
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFPI2 tissue factor pathway inhibitor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
USP15 ubiquitin specific peptidase 15
USP2 ubiquitin specific peptidase 2
VCPKMT valosin containing protein lysine (K) methyltransferase
VIPR1 vasoactive intestinal peptide receptor 1
WDR47 WD repeat domain 47
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZMYM5 zinc finger, MYM-type 5
ZXDC ZXD family zinc finger C

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADGRA3 adhesion G protein-coupled receptor A3
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
AGBL5 ATP/GTP binding protein-like 5
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AP1AR adaptor-related protein complex 1 associated regulatory protein
AP2M1 adaptor-related protein complex 2, mu 1 subunit
ARL5A ADP-ribosylation factor-like 5A
ATP13A2 ATPase type 13A2
AXIN1 axin 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAG3 BCL2-associated athanogene 3
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1ORF174 chromosome 1 open reading frame 174
CANT1 calcium activated nucleotidase 1
CCNG1 cyclin G1
CCNI cyclin I
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CSK c-src tyrosine kinase
CTNNBL1 catenin, beta like 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DROSHA drosha, ribonuclease type III
DSN1 DSN1, MIS12 kinetochore complex component
E2F6 E2F transcription factor 6
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EGR3 early growth response 3
EHD3 EH-domain containing 3
ERCC6L excision repair cross-complementation group 6-like
FAM102A family with sequence similarity 102, member A
FAM172A family with sequence similarity 172, member A
FAM20B family with sequence similarity 20, member B
FBXW12 F-box and WD repeat domain containing 12
FEN1 flap structure-specific endonuclease 1
FOXM1 forkhead box M1
FPGS folylpolyglutamate synthase
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GHR growth hormone receptor
GPR137B G protein-coupled receptor 137B
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA8 heat shock 70kDa protein 8
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
INSIG1 insulin induced gene 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCTD20 potassium channel tetramerization domain containing 20
KIAA0894 KIAA0894 protein
LIN37 lin-37 DREAM MuvB core complex component
LRRC49 leucine rich repeat containing 49
MAPKAP1 mitogen-activated protein kinase associated protein 1
MCM3AP-AS1 MCM3AP antisense RNA 1
MCRS1 microspherule protein 1
MELK maternal embryonic leucine zipper kinase
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MOCS2 molybdenum cofactor synthesis 2
MTIF2 mitochondrial translational initiation factor 2
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NINL ninein-like
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PDZK1 PDZ domain containing 1
PHTF1 putative homeodomain transcription factor 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
RGS19 regulator of G-protein signaling 19
RIC8B RIC8 guanine nucleotide exchange factor B
SACS sacsin molecular chaperone
SERINC5 serine incorporator 5
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC38A2 solute carrier family 38, member 2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
STARD7 StAR-related lipid transfer (START) domain containing 7
STK16 serine/threonine kinase 16
TATDN2 TatD DNase domain containing 2
TBC1D16 TBC1 domain family, member 16
TESK1 testis-specific kinase 1
TFRC transferrin receptor
TMEM187 transmembrane protein 187
TMEM243 transmembrane protein 243, mitochondrial
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TPST2 tyrosylprotein sulfotransferase 2
TRAK2 trafficking protein, kinesin binding 2
TXLNG taxilin gamma
UBL3 ubiquitin-like 3
UNC13B unc-13 homolog B (C. elegans)
UNKL unkempt family zinc finger-like
WDR13 WD repeat domain 13
WDR18 WD repeat domain 18
XBP1 X-box binding protein 1
ZDHHC4 zinc finger, DHHC-type containing 4
ZMAT3 zinc finger, matrin-type 3
ZNF248 zinc finger protein 248
ZNF692 zinc finger protein 692
ZNF8 zinc finger protein 8