ciclacillin-4536 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ciclacillin-4536 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ARID4B AT rich interactive domain 4B (RBP1-like)
ARMCX2 armadillo repeat containing, X-linked 2
ARPIN actin-related protein 2/3 complex inhibitor
ATAD5 ATPase family, AAA domain containing 5
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BATF basic leucine zipper transcription factor, ATF-like
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C1ORF116 chromosome 1 open reading frame 116
C1ORF61 chromosome 1 open reading frame 61
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CD58 CD58 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLCN7 chloride channel, voltage-sensitive 7
CLTCL1 clathrin, heavy chain-like 1
CNTNAP2 contactin associated protein-like 2
CPN2 carboxypeptidase N, polypeptide 2
CPZ carboxypeptidase Z
CSF1R colony stimulating factor 1 receptor
DCTN2 dynactin 2 (p50)
DMPK dystrophia myotonica-protein kinase
DPYSL4 dihydropyrimidinase-like 4
DVL3 dishevelled segment polarity protein 3
E2F4 E2F transcription factor 4, p107/p130-binding
ENOX2 ecto-NOX disulfide-thiol exchanger 2
FAM118A family with sequence similarity 118, member A
FBXO31 F-box protein 31
FGF5 fibroblast growth factor 5
FRMD1 FERM domain containing 1
GAL galanin/GMAP prepropeptide
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GAS1 growth arrest-specific 1
GLB1L galactosidase, beta 1-like
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GSK3A glycogen synthase kinase 3 alpha
HDAC11 histone deacetylase 11
HEMK1 HemK methyltransferase family member 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HEXIM1 hexamethylene bis-acetamide inducible 1
HIC2 hypermethylated in cancer 2
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
ICOSLG inducible T-cell co-stimulator ligand
IQCC IQ motif containing C
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JRK Jrk homolog (mouse)
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KIAA0040 KIAA0040
KIF17 kinesin family member 17
KLHL22 kelch-like family member 22
LDB1 LIM domain binding 1
LRP4 low density lipoprotein receptor-related protein 4
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NEB nebulin
NFRKB nuclear factor related to kappaB binding protein
NOP16 NOP16 nucleolar protein
NUP188 nucleoporin 188kDa
NUP88 nucleoporin 88kDa
NYNRIN NYN domain and retroviral integrase containing
OGFR opioid growth factor receptor
OSBP2 oxysterol binding protein 2
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFA platelet-derived growth factor alpha polypeptide
POU2F2 POU class 2 homeobox 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R7 protein phosphatase 1, regulatory subunit 7
PROX1 prospero homeobox 1
PRPH peripherin
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RALGDS ral guanine nucleotide dissociation stimulator
RASAL2 RAS protein activator like 2
REPS1 RALBP1 associated Eps domain containing 1
RNF6 ring finger protein (C3H2C3 type) 6
SCN11A sodium channel, voltage gated, type XI alpha subunit
SGK2 serum/glucocorticoid regulated kinase 2
SHOX2 short stature homeobox 2
SIK3 SIK family kinase 3
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SV2A synaptic vesicle glycoprotein 2A
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TEX14 testis expressed 14
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TLDC1 TBC/LysM-associated domain containing 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TOP3B topoisomerase (DNA) III beta
TUBA3C tubulin, alpha 3c
UNC93B1 unc-93 homolog B1 (C. elegans)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WT1 Wilms tumor 1
ZBTB43 zinc finger and BTB domain containing 43
ZC2HC1C zinc finger, C2HC-type containing 1C
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF141 zinc finger protein 141
ZNF500 zinc finger protein 500
ZNF573 zinc finger protein 573
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ADAM2 ADAM metallopeptidase domain 2
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMCX4 armadillo repeat containing, X-linked 4
ASPHD1 aspartate beta-hydroxylase domain containing 1
BTF3P12 basic transcription factor 3 pseudogene 12
C7ORF69 chromosome 7 open reading frame 69
CCDC106 coiled-coil domain containing 106
CCDC9 coiled-coil domain containing 9
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK3 cyclin-dependent kinase 3
CDKL3 cyclin-dependent kinase-like 3
CINP cyclin-dependent kinase 2 interacting protein
CPNE7 copine VII
CXCL3 chemokine (C-X-C motif) ligand 3
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOC2A double C2-like domains, alpha
DUSP8 dual specificity phosphatase 8
EDAR ectodysplasin A receptor
EFCAB2 EF-hand calcium binding domain 2
EFNB1 ephrin-B1
FANCC Fanconi anemia, complementation group C
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FURIN furin (paired basic amino acid cleaving enzyme)
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GJA8 gap junction protein, alpha 8, 50kDa
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRTP1 growth hormone regulated TBC protein 1
GTF2I general transcription factor IIi
HHLA3 HERV-H LTR-associating 3
HIST1H2AK histone cluster 1, H2ak
HIST1H2BN histone cluster 1, H2bn
HMOX1 heme oxygenase 1
HOXA6 homeobox A6
KDM8 lysine (K)-specific demethylase 8
KIAA0513 KIAA0513
KIFC1 kinesin family member C1
KRI1 KRI1 homolog (S. cerevisiae)
LOC100127972 uncharacterized LOC100127972
LOC729164 hCG1732469
LY6D lymphocyte antigen 6 complex, locus D
MBL1P mannose-binding lectin (protein A) 1, pseudogene
METTL16 methyltransferase like 16
MTA2 metastasis associated 1 family, member 2
MX1 MX dynamin-like GTPase 1
NAG18 NAG18 mRNA
NARFL nuclear prelamin A recognition factor-like
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NXPH4 neurexophilin 4
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PALMD palmdelphin
PDGFRL platelet-derived growth factor receptor-like
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLA2G1B phospholipase A2, group IB (pancreas)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLEKHO1 pleckstrin homology domain containing, family O member 1
PRB3 proline-rich protein BstNI subfamily 3
PRSS53 protease, serine, 53
PRSS8 protease, serine, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPS17P5 ribosomal protein S17 pseudogene 5
SAMD9 sterile alpha motif domain containing 9
SCGB2A2 secretoglobin, family 2A, member 2
SEPP1 selenoprotein P, plasma, 1
SERGEF secretion regulating guanine nucleotide exchange factor
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMR3A submaxillary gland androgen regulated protein 3A
SOBP sine oculis binding protein homolog (Drosophila)
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMSB15A thymosin beta 15a
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TUBG2 tubulin, gamma 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UGT8 UDP glycosyltransferase 8
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEZT vezatin, adherens junctions transmembrane protein
WDR76 WD repeat domain 76
WNT7A wingless-type MMTV integration site family, member 7A
YY2 YY2 transcription factor
ZBTB22 zinc finger and BTB domain containing 22
ZNF214 zinc finger protein 214
ZNF415 zinc finger protein 415
ZNF446 zinc finger protein 446
ZNF529 zinc finger protein 529
ZNF76 zinc finger protein 76