chylomicron Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues. (Gene Ontology, GO_0042627)
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Genes

153 proteins co-occuring with the chylomicron cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
LPL lipoprotein lipase 3.4971
APOB apolipoprotein B 2.8274
APOE apolipoprotein E 2.5777
MTTP microsomal triglyceride transfer protein 2.11366
LPA lipoprotein, Lp(a) 1.97557
MYDGF myeloid-derived growth factor 1.94461
APOC2 apolipoprotein C-II 1.86005
APOC3 apolipoprotein C-III 1.82524
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 1.80573
APOA4 apolipoprotein A-IV 1.70137
LDLR low density lipoprotein receptor 1.61588
SAR1B secretion associated, Ras related GTPase 1B 1.5531
APOA1 apolipoprotein A-I 1.51751
INS insulin 1.48305
PNLIP pancreatic lipase 1.42317
NPC1L1 NPC1-like 1 1.35594
LIPC lipase, hepatic 1.31035
FABP2 fatty acid binding protein 2, intestinal 1.29585
LCAT lecithin-cholesterol acyltransferase 1.29371
CETP cholesteryl ester transfer protein, plasma 1.28303
APOA2 apolipoprotein A-II 1.18543
ALB albumin 1.18235
APOA5 apolipoprotein A-V 1.17876
GIP gastric inhibitory polypeptide 1.13012
SCARB1 scavenger receptor class B, member 1 1.06448
ANGPTL4 angiopoietin-like 4 0.992204
COG2 component of oligomeric golgi complex 2 0.962627
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 0.960227
ANGPTL3 angiopoietin-like 3 0.941636
CEL carboxyl ester lipase 0.932658
LTF lactotransferrin 0.889321
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 0.889321
DGAT1 diacylglycerol O-acyltransferase 1 0.88286
TGFA transforming growth factor, alpha 0.880094
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.878712
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.870885
PLTP phospholipid transfer protein 0.834138
PYY peptide YY 0.789191
CD36 CD36 molecule (thrombospondin receptor) 0.776384
GCG glucagon 0.775928
LIPG lipase, endothelial 0.757707
CLPS colipase, pancreatic 0.746833
SCARB2 scavenger receptor class B, member 2 0.721242
ARL8A ADP-ribosylation factor-like 8A 0.713238
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.710136
IRF6 interferon regulatory factor 6 0.699543
PCSK9 proprotein convertase subtilisin/kexin type 9 0.692516
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.692516
APOC1 apolipoprotein C-I 0.688139
APOBR apolipoprotein B receptor 0.683771
ACSS2 acyl-CoA synthetase short-chain family member 2 0.667693
SRR serine racemase 0.660776
SCARF1 scavenger receptor class F, member 1 0.644858
VAMP7 vesicle-associated membrane protein 7 0.644429
TGM4 transglutaminase 4 0.633732
LMF1 lipase maturation factor 1 0.626057
RBP1 retinol binding protein 1, cellular 0.610355
HMGA2 high mobility group AT-hook 2 0.609932
FASN fatty acid synthase 0.607818
LIPE lipase, hormone-sensitive 0.607818
ZNF664 zinc finger protein 664 0.59896
CES1 carboxylesterase 1 0.595593
SREBF1 sterol regulatory element binding transcription factor 1 0.585523
ARFRP1 ADP-ribosylation factor related protein 1 0.567585
LEP leptin 0.566338
APOH apolipoprotein H (beta-2-glycoprotein I) 0.553491
RBP2 retinol binding protein 2, cellular 0.546885
USF1 upstream transcription factor 1 0.541117
TTPA tocopherol (alpha) transfer protein 0.523067
SDC2 syndecan 2 0.518981
FRMD5 FERM domain containing 5 0.518573
GLP1R glucagon-like peptide 1 receptor 0.50757
VLDLR very low density lipoprotein receptor 0.499853
MANF mesencephalic astrocyte-derived neurotrophic factor 0.4958
SOAT1 sterol O-acyltransferase 1 0.489327
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 0.463198
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.456809
LYPLAL1 lysophospholipase-like 1 0.451631
DPP4 dipeptidyl-peptidase 4 0.439333
ELOVL5 ELOVL fatty acid elongase 5 0.432618
PPARA peroxisome proliferator-activated receptor alpha 0.427497
TSKU tsukushi, small leucine rich proteoglycan 0.41221
SOAT2 sterol O-acyltransferase 2 0.410649
ARL5A ADP-ribosylation factor-like 5A 0.403248
TTR transthyretin 0.39471
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 0.385436
ALPI alkaline phosphatase, intestinal 0.384665
RBP5 retinol binding protein 5, cellular 0.380429
ARL1 ADP-ribosylation factor-like 1 0.374283
SREBF2 sterol regulatory element binding transcription factor 2 0.373899
CRP C-reactive protein, pentraxin-related 0.368919
DGAT2 diacylglycerol O-acyltransferase 2 0.359752
HP haptoglobin 0.347587
CSN1S1 casein alpha s1 0.336619
HPR haptoglobin-related protein 0.330966
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 0.324201
GC group-specific component (vitamin D binding protein) 0.323075
PON1 paraoxonase 1 0.317082
GOSR1 golgi SNAP receptor complex member 1 0.310732
C3 complement component 3 0.304027
LSR lipolysis stimulated lipoprotein receptor 0.302168
SEC23IP SEC23 interacting protein 0.301425
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.298084
CALCOCO2 calcium binding and coiled-coil domain 2 0.293637
PPARG peroxisome proliferator-activated receptor gamma 0.288091
BET1 Bet1 golgi vesicular membrane trafficking protein 0.287721
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 0.282558
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 0.272267
C4BPA complement component 4 binding protein, alpha 0.266408
PLG plasminogen 0.255107
HNF4A hepatocyte nuclear factor 4, alpha 0.250751
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 0.250026
SEC24B SEC24 family member B 0.249664
P4HB prolyl 4-hydroxylase, beta polypeptide 0.246046
PON3 paraoxonase 3 0.240996
JTB jumping translocation breakpoint 0.233101
SAA1 serum amyloid A1 0.231672
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 0.231672
TCHH trichohyalin 0.228819
LRP2 low density lipoprotein receptor-related protein 2 0.228108
HIBADH 3-hydroxyisobutyrate dehydrogenase 0.223143
F2 coagulation factor II (thrombin) 0.222083
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 0.21646
HRASLS5 HRAS-like suppressor family, member 5 0.21228
ERN2 endoplasmic reticulum to nucleus signaling 2 0.209858
KLHL12 kelch-like family member 12 0.209169
DLL1 delta-like 1 (Drosophila) 0.204039
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.201672
CCK cholecystokinin 0.199325
TRIM47 tripartite motif containing 47 0.1921
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.189539
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.188274
ACLY ATP citrate lyase 0.185777
PCSK5 proprotein convertase subtilisin/kexin type 5 0.183025
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 0.177439
AMY2A amylase, alpha 2A (pancreatic) 0.176587
SDC1 syndecan 1 0.174635
SEC13 SEC13 homolog (S. cerevisiae) 0.173543
CLEC3B C-type lectin domain family 3, member B 0.173273
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 0.17141
ELOVL2 ELOVL fatty acid elongase 2 0.16935
GYS1 glycogen synthase 1 (muscle) 0.167611
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 0.16477
F12 coagulation factor XII (Hageman factor) 0.161905
PXDN peroxidasin 0.160658
WRAP73 WD repeat containing, antisense to TP73 0.143403
GML glycosylphosphatidylinositol anchored molecule like 0.141751
PRKCD protein kinase C, delta 0.141351
STAB1 stabilin 1 0.140087
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 0.14005
SPINK5 serine peptidase inhibitor, Kazal type 5 0.139003
CCL2 chemokine (C-C motif) ligand 2 0.136626
CHL1 cell adhesion molecule L1-like 0.136445